Understanding GALNT14: A Potential Drug Target and Biomarker (G79623)

Target Name: GALNT14

NCBI ID: G79623

GALNT14

Understanding GALNT14: A Potential Drug Target and Biomarker

GALNT14 (GalNac-T14) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker. Its unique structure and function have made it an attractive target for researchers to study.

GALNT14 is a small RNA molecule that is known for its ability to interact with the protein kinase kinase A (PKA) to regulate its activity. PKA is a protein that is involved in many different cellular processes, including cell growth, differentiation, and survival. By interacting with PKA, GALNT14 has been shown to play a role in regulating the activity of many different genes.

One of the unique features of GALNT14 is its structure. It is a small RNA molecule that is made up of only 14 amino acids. Despite its small size, GALNT14 has a highly conserved structure and is able to interact with PKA in a stable manner. This stability is important for GALNT14 to function as a drug target and biomarker.

GALNT14 has been shown to interact with PKA in a variety of cellular contexts. For example, GALNT14 has been shown to interact with PKA in the cytoplasm of cells, which is the fluid that surrounds the cells. This interaction suggests that GALNT14 may be involved in regulating the activity of PKA in the cytoplasm, which could have important implications for the functions of the cell.

Another context in which GALNT14 has been shown to interact with PKA is in the nucleus. The nucleus is the central structural component of a cell and is involved in the regulation of many different cellular processes. , which suggests that it may be involved in regulating the activity of PKA in the nucleus.

In addition to its interactions with PKA, GALNT14 has also been shown to play a role in the regulation of gene expression. GALNT14 has been shown to interact with the RNA polymerase II (RNA-II), which is a protein that is involved in the regulation of gene expression. This interaction suggests that GALNT14 may be involved in the regulation of gene expression by RNA-II.

GALNT14's unique structure and function have made it an attractive target for researchers to study. Its ability to interact with PKA and RNA-II suggests that it may be a useful drug target and biomarker. Further research is needed to fully understand the role of GALNT14 in cellular processes and its potential as a drug.

Protein Name: Polypeptide N-acetylgalactosaminyltransferase 14

Functions: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays activity toward mucin-derived peptide substrates such as Muc2, Muc5AC, Muc7, and Muc13 (-58). May be involved in O-glycosylation in kidney

The "GALNT14 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GALNT14 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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