GALM: A Key Enzyme in Galactose Metabolism (G130589)

Target Name: GALM

NCBI ID: G130589

GALM

GALM: A Key Enzyme in Galactose Metabolism

GALM, or Galactose mutarotase, is a protein that is found in the human body. It is a key enzyme that is involved in the metabolism of galactose, which is a type of sugar that is found in milk and other dairy products. Galactose is normally broken down into glucose by the body, but GALM helps to regulate the breakdown of galactose into glucose.

GALM is a protein that is made up of 11 different amino acids. It has a molecular weight of 17 kDa and a pre-alpha-subunit molecular weight of 16 kDa. GALM is found in various tissues throughout the body, including the liver, pancreas, and muscle. It is also found in the placenta, which is the tissue that carries nutrients from the mother to the baby in the womb.

GALM is involved in the breakdown of galactose into glucose. This process is called galactose metabolism, and it is an important part of the body's metabolism of the nutrients that it needs to function. Galactose is normally broken down into glucose by the body, but GALM helps to regulate the breakdown of galactose into glucose. This is important because glucose is the body's primary source of energy, and it is necessary for the body to function properly.

GALM is also involved in the regulation of the levels of glucose in the body. It helps to control the amount of glucose that enters the bloodstream, which is important for maintaining the proper balance of glucose in the body. If the levels of glucose in the body become too high or too low, it can cause a variety of health problems, including diabetes.

GALM is a protein that is involved in many different processes in the body. It is important for the proper functioning of the body and for maintaining the health of the cells. Unfortunately, there is some research that suggests that GALM may also be a potential drug target or biomarker for a variety of diseases, including cancer, obesity, and neurodegenerative diseases.

In conclusion, GALM is a protein that is found in the human body and is involved in the breakdown of galactose into glucose. It is also involved in the regulation of the levels of glucose in the body and is a potential drug target or biomarker for a variety of diseases. Further research is needed to fully understand the role of GALM in the body and to develop effective treatments for the diseases that are associated with it.

Protein Name: Galactose Mutarotase

Functions: Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism (PubMed:12753898). Beta-D-galactose is metabolized in the liver into glucose 1-phosphate, the primary metabolic fuel, by the action of four enzymes that constitute the Leloir pathway: GALM, GALK1 (galactokinase), GALT (galactose-1-phosphate uridylyltransferase) and GALE (UDP-galactose-4'-epimerase) (PubMed:30451973). Involved in the maintenance of the equilibrium between the beta- and alpha-anomers of galactose, therefore ensuring a sufficient supply of the alpha-anomer for GALK1 (PubMed:12753898). Also active on D-glucose although shows a preference for galactose over glucose (PubMed:12753898)

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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