GARIN3: A Potential Drug Target and Biomarker for Golgi-associated Rab2 Interactor Protein 3

Target Name: GARIN3

NCBI ID: G153745

GARIN3

GARIN3: A Potential Drug Target and Biomarker for Golgi-associated Rab2 Interactor Protein 3

Golgi-associated Rab2 (GARIN2) interactor protein 3 (GARIN3) is a protein that plays a critical role in the regulation of cell signaling pathways, including the T-cell receptor (TCR) signaling pathway. GARIN3 is a 21-kDa protein that is expressed in various tissues and cell types, including human T cells, mouse peritoneal macrophages, and human endothelial cells. GARIN3 has been shown to interact with the protein Rab2, which is a GTPase that regulates cell signaling pathways, including the T-cell receptor ( TCR) signaling pathway.

GARIN3 has been shown to play a critical role in the regulation of T-cell development and function. For example, GARIN3 has been shown to promote the expansion and differentiation of human T cells, and to regulate the articulation of T-cell memory and effector functions. In addition, GARIN3 has been shown to play a critical role in the regulation of immune cell function, including the regulation of dendritic cell function and the modulation of T-cell responses.

GARIN3 has also been shown to play a critical role in the regulation of cell signaling pathways that are involved in cancer progression. For example, GARIN3 has been shown to promote the migration and invasion of cancer cells, and to contribute to the development of cancer stem cells. In addition, GARIN3 has been shown to play a critical role in the regulation of cell signaling pathways that are involved in neurodegenerative diseases, including Alzheimer's disease.

GARIN3 is also a potential drug target, as several studies have shown that GARIN3 can be targeted by small molecules, including inhibitors of the Rab2 GTPase activity (6) and of the GARIN3-Rab2 interaction. In addition, GARIN3 has been shown to be involved in several cellular processes that are involved in the development of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. Therefore, GARIN3 may be a valuable biomarker and a potential drug target for a variety of diseases.

In conclusion, GARIN3 is a protein that plays a critical role in the regulation of cell signaling pathways, including the T-cell receptor (TCR) signaling pathway. GARIN3 is expressed in various tissues and cell types, including human T cells, mouse peritoneal macrophages , and human endothelial cells. GARIN3 has been shown to interact with the protein Rab2, which is a GTPase that regulates cell signaling pathways. GARIN3 has been shown to promote the expansion and differentiation of human T cells, and to regulate the junction of T- cell memory and effector functions. In addition, GARIN3 has also been shown to play a critical role in the regulation of immune cell function, including the regulation of dendritic cell function and the modulation of T-cell responses. GARIN3 has also been shown to promote the migration and invasion of cancer cells and to contribute to the development of cancer stem cells. In addition, GARIN3 has been shown to play a critical role in the regulation of cell signaling pathways that are involved in cancer progression, neurodegenerative diseases, and autoimmune diseases. Therefore, GARIN3 may be a valuable biomarker and a potential drug target for a variety of diseases.

Protein Name: Golgi Associated RAB2B Interactor Family Member 3

Functions: May be involved in RNA biogenesis

The "GARIN3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GARIN3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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