SEC24C: A Protein Involved in DNA Replication and Regulation (G9632)

Target Name: SEC24C

NCBI ID: G9632

SEC24C

SEC24C: A Protein Involved in DNA Replication and Regulation

SEC24C, also known as SEC24 homolog C, is a protein that is found in various organisms including bacteria, archaea, and eukaryotes. It is a member of the SEC24 family of proteins, which are involved in various cellular processes such as DNA replication, transcription, and regulation. SEC24C is a homolog of the SEC24 gene, which is located on chromosome 24 of the human genome.

One of the key functions of SEC24C is its role in the replication of DNA. It is a component of the DNA replication machinery, which is responsible for copying the genetic information from one generation to the next. In addition to its role in replication, SEC24C is also involved in the regulation of gene expression. It has been shown to play a role in the regulation of gene expression by binding to specific DNA sequences and interacting with proteins such as RNA polymerase II.

Another function of SEC24C is its role in the regulation of cell growth and division. It is involved in the regulation of cell size and in the formation of organelles during the process of mitosis. In addition, SEC24C is also involved in the regulation of cell division by binding to the protein checkpoint, which is a protein that helps to ensure that cells divide in a orderly and accurate manner.

In addition to its role in cell biology, SEC24C is also a potential drug target. Several studies have shown that SEC24C plays a role in the regulation of various cellular processes, including cell growth, replication, and differentiation. As a result, SEC24C is a potential target for small molecules that can be used to inhibit or activate these processes.

One of the most promising strategies for targeting SEC24C is the use of small molecules that can modulate its activity. These small molecules can be administered to cells and interact with SEC24C to either inhibit or activate its activity. For example, one class of small molecules that have been shown to interact with SEC24C is called IDMs (inositol derivatives). These small molecules have been shown to inhibit the activity of SEC24C and to stabilize the complex between SEC24C and RNA polymerase II.

Another class of small molecules that have been shown to interact with SEC24C are the N-pyruvate derivatives. These small molecules have been shown to activate the activity of SEC24C and to promote the formation of the complex between SEC24C and RNA polymerase II.

In conclusion, SEC24C is a protein that is involved in various cellular processes including DNA replication, transcription, and regulation. It is a member of the SEC24 family of proteins and is a potential drug target. The use of small molecules that can modulate its activity is a promising strategy for studying and targeting SEC24C. Further research is needed to fully understand the role of SEC24C in cell biology and its potential as a drug target.

Protein Name: SEC24 Homolog C, COPII Coat Complex Component

Functions: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (PubMed:10214955, PubMed:17499046, PubMed:18843296, PubMed:20427317). Plays a central role in cargo selection within the COPII complex and together with SEC24D may have a different specificity compared to SEC24A and SEC24B (PubMed:17499046, PubMed:20427317, PubMed:18843296). May more specifically package GPI-anchored proteins through the cargo receptor TMED10 (PubMed:20427317). May also be specific for IxM motif-containing cargos like the SNAREs GOSR2 and STX5 (PubMed:18843296)

The "SEC24C Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SEC24C comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
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•   related combination drugs;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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