SECISBP2: A Potential Drug Target and Biomarker (G79048)

Target Name: SECISBP2

NCBI ID: G79048

SECISBP2

SECISBP2: A Potential Drug Target and Biomarker

Introduction

SECISBP2 (SECIS-binding protein 2) is a protein that is expressed in various tissues and cells of the human body. It is a member of the SECISBP family, which includes proteins that play a critical role in the regulation of cell signaling pathways. Several studies have identified SECISBP2 as a potential drug target and biomarker, and further research is needed to determine its full potential.

The ProteinsecisBP2 (SECIS-binding protein 2)

SECISBP2 is a 120-kDa protein that is expressed in various tissues and cells of the human body. It is characterized by a N-terminal 伪-helix, a C-terminal conserved 尾-sheet, and a C-terminal long amine group acid sequence. SECISBP2 plays an important role in cell signaling pathways and is one of the key players in multiple signaling pathways.

Biological functions of SECISBP2

SECISBP2 plays an important role in a variety of physiological processes. SECISBP2 plays a crucial role in cell proliferation and apoptosis. Studies have shown that SECISBP2 regulates the formation and disappearance of spindles during the cell cycle and plays an important role in the assembly and disassembly of spindle microtubules. In addition, SECISBP2 is also involved in the regulation of apoptosis and is one of the key players in the apoptosis signaling pathway.

Pharmacological significance of SECISBP2

SECISBP2 is a potential drug target. Studies have shown that SECISBP2 is overexpressed in a variety of tumor cells and plays an important role in tumor growth and metastasis. In addition, SECISBP2 is also closely related to the occurrence and development of various diseases, such as neurodegenerative diseases, diabetes and obesity. Therefore, SECISBP2 is considered a potential drug target.

Detection of SECISBP2

Currently, there are two main methods for detecting SECISBP2: Western blot and immunohistochemistry. Western blot is a commonly used detection method that can detect the protein expression level of SECISBP2. Immunohistochemistry is a method to directly observe protein expression in cells, and can detect the expression of SECISBP2 in cells.

Biological activity of SECISBP2

SECISBP2 plays an important role in a variety of physiological processes and has a variety of biological activities. Studies have shown that SECISBP2 can regulate cell proliferation and apoptosis and participate in the regulation of cell signaling pathways. In addition, SECISBP2 can also participate in cell adhesion, migration and tumor cell invasion.

Conclusion

SECISBP2 is a potential drug target and an important biomarker. further research is needed to determine its full potential as a drug target and biomarker.

Protein Name: SECIS Binding Protein 2

Functions: Binds to the SECIS element in the 3'-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
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