Understanding PSMD6: Potential Drug Target and Biomarker (G9861)

Target Name: PSMD6

NCBI ID: G9861

PSMD6

Understanding PSMD6: Potential Drug Target and Biomarker

PSMD6 (Protein Sequence Modeling and Databasing, version 6) is a protein coding gene that has been identified as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. The gene is located on chromosome 16 and encodes a protein known as PSMD6, which is involved in the process of protein synthesis and degradation.

PSMD6 has been shown to be involved in a number of cellular processes that are important for human health, including the regulation of cell death, the stress response, and the immune response. It has also been linked to a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the key challenges in studying PSMD6 and its potential drug targets is the complexity of its function and the lack of clear consensus on its exact role in the body. However, research into its various functions and interactions with other proteins suggests that it plays an important role in the regulation of cellular processes that are critical for human health and the development of disease.

One of the key functions of PSMD6 is its role in the regulation of cell death. In cancer cells, PSMD6 has been shown to play a role in the development and progression of cancer. For example, studies have shown thatPSMD6 levels are elevated in human cancer cells and that inhibiting its activity can lead to the inhibition of cancer cell growth and the death of cancer cells.

PSMD6 is also involved in the regulation of the immune response, which is important for maintaining human health and preventing the development of diseases such as autoimmune disorders. The protein has been shown to be involved in the development and regulation of dendritic cells, which are important for the recruitment of immune cells to the site of an infection or inflammation.

In addition to its role in the regulation of cell death and the immune response, PSMD6 is also involved in the regulation of protein synthesis and degradation. This is important for maintaining the stability of cellular proteins, which is critical for the proper functioning of cells and the development and progression of diseases.

The potential drug targets for PSMD6 are vast and varied. Some studies have suggested that PSMD6 could be a potential target for cancer therapies, including inhibitors of its activity that could lead to the inhibition of cancer cell growth and the death of cancer cells. Other studies have suggested that PSMD6 could be a potential target for neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease, due to its involvement in the regulation of the immune response and the development and regulation of dendritic cells.

In addition to its potential as a drug target, PSMD6 has also been identified as a potential biomarker for a number of diseases. For example, studies have shown that PSMD6 levels are elevated in the brains of individuals with Alzheimer's disease and that inhibiting its activity in these individuals may lead to the regression of neurodegeneration. This suggests that PSMD6 may be an effective biomarker for Alzheimer's disease and could be used as a target for therapies aimed at treating this disease.

Overall, PSMD6 is a protein coding gene that has been shown to be involved in a number of cellular processes that are important for human health and the development of disease. Its potential drug targets and biomarker status make it an attractive target for further research and the development of new therapies. Further studies are needed to fully understand its functions and its potential as a drug and biomarker.

Protein Name: Proteasome 26S Subunit, Non-ATPase 6

Functions: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair

The "PSMD6 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PSMD6 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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