LOC100131943: A Drug Target / Disease Biomarker (G100131943)
LOC100131943: A Drug Target / Disease Biomarker
LOC100131943 is a protein that is expressed in various tissues throughout the body, including the brain, heart, kidneys, and liver. It is a member of the G protein-coupled receptor (GPCR) family, which is a large superfamily of transmembrane proteins that play a critical role in cellular signaling.
LOC100131943 is characterized by its long extracellular domain, which contains a unique farnesylated cysteine residue. This cysteine residue is known as a Lysine 276 (L276) mutation, which is a genetic modification that can alter the stability and activity of the protein.
The L276 mutation has been shown to have a significant impact on the function of LOC100131943. In studies using cell-based assays and in vitro experiments, researchers have shown that the L276 mutation can alter the stability and localization of the protein, as well as its interactions with other proteins.
One of the most interesting aspects of LOC100131943 is its potential as a drug target. The L276 mutation has been shown to alter the activity of the protein, which raises the possibility that it may be a useful target for small molecules that can modulate its function.
In addition to its potential as a drug target, LOC100131943 is also a promising biomarker for a variety of diseases. The protein is expressed in many different tissues and has been shown to be involved in a number of cellular signaling pathways, including the regulation of cell growth, differentiation, and survival.
Research into LOC100131943 has also focused on its potential role in the development and progression of a variety of diseases, including cancer. Studies have shown that LOC100131943 is involved in the regulation of cell proliferation and has been implicated in the development of many types of cancer.
Overall, LOC100131943 is a protein that has significant potential as a drug target and as a biomarker for a variety of diseases. Its unique farnesylated cysteine residue and its involvement in cellular signaling pathways make it an attractive target for small molecules, and its involvement in the regulation of many different cellular processes makes it a valuable tool for the study of disease.
Protein Name: Uncharacterized LOC100131943
More Common Targets
LOC100132004 | LOC100132062 | LOC100132077 | LOC100132078 | LOC100132249 | LOC100132287 | LOC100132356 | LOC100132609 | LOC100132626 | LOC100132651 | LOC100132686 | LOC100132741 | LOC100132781 | LOC100132797 | LOC100133077 | LOC100133165 | LOC100133177 | LOC100133284 | LOC100133331 | LOC100133920 | LOC100134317 | LOC100134368 | LOC100134391 | LOC100134868 | LOC100190986 | LOC100233156 | LOC100240728 | LOC100240734 | LOC100240735 | LOC100271840 | LOC100272216 | LOC100272217 | LOC100286922 | LOC100287036 | LOC100287290 | LOC100287329 | LOC100287413 | LOC100287792 | LOC100287834 | LOC100287846 | LOC100287944 | LOC100288069 | LOC100288162 | LOC100288208 | LOC100288637 | LOC100288656 | LOC100289230 | LOC100289283 | LOC100289308 | LOC100289333 | LOC100289361 | LOC100289470 | LOC100289473 | LOC100289495 | LOC100289511 | LOC100289561 | LOC100289580 | LOC100289656 | LOC100293211 | LOC100294145 | LOC100335030 | LOC100419773 | LOC100420587 | LOC100421561 | LOC100505498 | LOC100505502 | LOC100505585 | LOC100505664 | LOC100505715 | LOC100505716 | LOC100505841 | LOC100505912 | LOC100505915 | LOC100505978 | LOC100506023 | LOC100506071 | LOC100506076 | LOC100506124 | LOC100506207 | LOC100506236 | LOC100506274 | LOC100506281 | LOC100506379 | LOC100506403 | LOC100506422 | LOC100506444 | LOC100506446 | LOC100506472 | LOC100506474 | LOC100506499 | LOC100506514 | LOC100506532 | LOC100506606 | LOC100506634 | LOC100506639 | LOC100506667 | LOC100506730 | LOC100506974 | LOC100507002 | LOC100507006