Target Name: SHROOM1
NCBI ID: G134549
Review Report on SHROOM1 Target / Biomarker Content of Review Report on SHROOM1 Target / Biomarker
SHROOM1
Other Name(s): SHRM1_HUMAN | Protein Shroom1 (isoform 1) | Shroom family member 1, transcript variant 1 | shroom family member 1 | SHROOM1 variant 1 | Apical protein 2 | KIAA1960 | Protein Shroom1 | APXL2 | apical protein 2

SHROOM1: A Protein Targeted for Cancer, Neurodegenerative Diseases and Autoimmune Disorders

SHROOM1 (SHRM1_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, liver, and pancreas. It is a member of the superfamily of RNA-protein interactions and is involved in various cellular processes.

Recent studies have identified SHROOM1 as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This is due to its involvement in various signaling pathways and its expression in several disease-related tissues.

One of the key functions of SHROOM1 is its role in the regulation of gene expression. It is a transcription factor that can interact with various DNA sequences to control the expression of genes. This interaction between SHROOM1 and DNA sequences allows for the regulation of a wide range of cellular processes, including cell growth, apoptosis, and inflammation.

In addition to its role in gene expression, SHROOM1 is also involved in the regulation of protein translation. It has been shown to play a role in the regulation of protein synthesis and can interact with various cellular structures to control the rate at which proteins are produced.

The expression of SHROOM1 is also regulated by various factors, including DNA methylation, histone modification, and post-transcriptional modification. These factors can alter the stability and localization of SHROOM1, and can influence its function in various cellular processes.

The potential drug targets for SHROOM1 are vast, as it is involved in a wide range of cellular processes that are relevant to many diseases. Some of the potential targets for SHROOM1 include transcription factors, protein synthesis factors, and signaling pathways that are involved in cancer , neurodegenerative diseases, and autoimmune disorders.

In cancer, SHROOM1 has been shown to be involved in the regulation of various cellular processes that are relevant to tumor growth and progression. For example, SHROOM1 has been shown to play a role in the regulation of cell cycle progression, which is the process by which cells grow and divide. It has been shown to interact with the protein kinase kinase B (PKB) and can inhibit its activity, leading to the inhibition of cell proliferation.

In addition to its role in cell cycle progression, SHROOM1 has also been shown to be involved in the regulation of apoptosis, which is the process by which cells undergo programmed cell death. It has been shown to interact with the protein caspase-3 (Cas3 ) and can inhibit its activity, leading to the inhibition of apoptosis.

In neurodegenerative diseases, SHROOM1 has been shown to be involved in the regulation of various cellular processes that are relevant to the progression of neurodegeneration. For example, SHROOM1 has been shown to play a role in the regulation of neurotransmitter synthesis and release, which is involved in the regulation of mood, pain, and other neurological symptoms.

In addition to its role in neurotransmitter synthesis and release, SHROOM1 has also been shown to be involved in the regulation of synaptic plasticity, which is the ability of the brain to change and adapt over time. It has been shown to interact with the protein brain -derived neurotrophic factor (BDNF) and can enhance its activity, leading to the regulation of synaptic plasticity.

In autoimmune disorders, SHROOM1 has been shown to be involved in the regulation of various cellular processes that are relevant to the development of autoimmune diseases. For example, SHROOM1 has been shown to play a role in the regulation of the immune response, which is involved in the regulation of inflammation and immune cell function.

In addition to its role in the regulation of the immune response, SHROOM1 has also been shown to be involved in the regulation of inflammation

Protein Name: Shroom Family Member 1

Functions: May be involved in the assembly of microtubule arrays during cell elongation

The "SHROOM1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SHROOM1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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