Vogt-Koyanagi-Harada Syndrome
About the Disease
Vogt-Koyanagi-Harada Disease, also known as uveomeningoencephalitic syndrome, is related to uveitis and pars planitis. An important gene associated with Vogt-Koyanagi-Harada Disease is PTPN22 (Protein Tyrosine Phosphatase Non-Receptor Type 22), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Bevacizumab and Triamcinolone have been mentioned in the context of this disorder. Affiliated tissues include eye, skin and retina, and related phenotypes are sensorineural hearing impairment and cognitive impairment
Common Targets
G137196 | Tyrosine-Protein Kinases Src (nonspecified subtype) | G101928791 | G284825 | G1235 | G54665 | G102467213 | G107986764 | G10533 | G105377441 | G3426 | G3932 | G3105 | G400867 | G10866 | G283575 | G101929019 | G105375523 | G201266 | G107987121 | G7188 | G1611 | G121838 | G105370982 | G30009 | G3605 | G958 | G4846 | G105371006 | G960 | G100874048 | G102659288 | G9474 | G3586 | G55054 | G728597 | G105369325 | G285484 | G105375746 | G400952 | G101928136 | G400957 | G11116 | G105375911 | P5867 | G105369568 | G7010 | G221178 | G100130476 | G9448 | G406958 | G285577 | G150577 | G284119 | G3458 | G11184 | G729993 | G4843 | G7128 | G3717 | G51300 | G107984118 | G23130 | G55191 | G152225 | G102724900 | G105369735 | G105374364 | G105374410 | G404663 | G285626 | G26191 | G2842 | G3716 | G102724940 | G105376230 | G283876 | G406938 | G4282 | G3565 | G103689918 | G23274 | G3119 | G105371887 | G3107 | G2625 | G8927 | G107984764 | G6347 | G105374624 | G100507267 | G105376481 | G7040 | G105369850 | G107984884 | G100505566 | G107984903 | G101927324 | G6774 | G10318 | G6890 | G101927334 | G105376626 | G149233 | G83734 | G101927354 | G101930275 | G285834 | G10758 | G50943 | G3123 | G6097 | G101927592 | G105379031 | G3106 | G6696 | G2113 | G8408 | G100132677 | G7248 | G101927650 | G27 | G102723828 | G5820 | G100506023 | G105370401 | G101927745 | G400757
The "Target / Biomarker Review Report" is a comprehensive and customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about the Target(s) / Biomarker(s) of your choice related to Vogt-Koyanagi-Harada Syndrome, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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