Wilson's Disease
About the Disease
Wilson Disease, also known as hepatolenticular degeneration, is related to disorder of copper metabolism and choreatic disease, and has symptoms including abdominal pain, back pain and constipation. An important gene associated with Wilson Disease is ATP7B (ATPase Copper Transporting Beta), and among its related pathways/superpathways are Ferroptosis and Detoxification of Reactive Oxygen Species. The drugs Zinc cation and Choline have been mentioned in the context of this disorder. Affiliated tissues include Liver, eye and brain, and related phenotypes are intellectual disability and failure to thrive
Common Targets
G5052 | G80339 | G10652 | G4257 | G3383 | G4259 | G3480 | G50488 | P6058 | G10454 | G23040 | G5770 | G7015 | G5590 | G84700 | G79755 | G782 | G2949 | G7481 | P5761 | P16126 | G84146 | G10014 | G2201 | G51085 | G2950 | G25823 | G10801 | G2531 | G11014 | G5314 | G4763 | G25828 | Amyloid beta A4 precursor protein-binding family (APP-BP) (nonspecified subtype) | G338707 | Vascular endothelial growth factor receptor (VEGFR) (nonspecified subtype) | G182 | G4501 | G1080 | G3141 | G84317 | G1051 | G540 | G164832 | G10599 | G351 | G150684 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | G177 | G7054 | G2275 | G60312 | G2263 | G3899 | G10013 | G10165 | G2954 | G81559 | G6647 | G202915 | G2247 | G392617 | G60490 | G54890 | G392862 | G2766 | G6493 | G1317 | G768239 | G8912 | G3077 | G816 | G5604 | G64855 | P5760 | G9644 | G2946 | G8379 | G51168
The "Target / Biomarker Review Report" is a comprehensive and customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about the Target(s) / Biomarker(s) of your choice related to Wilson's Disease, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
Other Diseases
Wiskott-Aldrich Syndrome | Withdrawal Syndrome | Wolcott-Rallison Syndrome | Wolff-Parkinson-White Syndrome | Wolfram Syndrome | Wolfram Syndrome 2 | Wolman Disease | Woodhouse-Sakati Syndrome | X-linked Acrogigantism | X-linked Charcot-Marie-Tooth Disease | X-linked Creatine Transporter Deficiency | X-linked Myotubular Myopathy | X-linked Sideroblastic Anemia | Xeroderma Pigmentosum | Xeroderma Pigmentosum Variant Type | Yellow Fever | Zellweger Syndrome | Zimmermann-Laband Syndrome | Zollinger-Ellison Syndrome | Zygomycosis
