Target Name: SHISA9
NCBI ID: G729993
Review Report on SHISA9 Target / Biomarker Content of Review Report on SHISA9 Target / Biomarker
SHISA9
Other Name(s): Shisa family member 9, transcript variant 1 | Shisa family member 9 | Cystine-knot AMPAR modulating protein | SHISA9 variant X3 | shisa family member 9 | cystine-knot AMPAR modulating protein | Protein shisa-9 precursor | shisa homolog 9 | SHSA9_HUMAN | Protein shisa-9 (isoform 1) | CKAMP44 | Protein shisa-9 | SHISA9 variant 1

SHISA9: A Potential Drug Target and Biomarker

Shisa family member 9 (SHISA9) is a gene that encodes a protein located in the endoplasmic reticulum (ER) of eukaryotic cells. The SHISA9 protein has unique features that make it an attractive candidate for drug targeting and biomarker research. This article will provide an overview of SHISA9, its potential drug targets, and its potential as a biomarker.

Potential Drug Targets

SHISA9 has several potential drug targets due to its unique structure and its involvement in various cellular processes. One of the potential drug targets for SHISA9 is the FBN1 gene, which encodes a protein called fibrillin-1. FBN1 is a protein that is involved in the regulation of cell growth, differentiation, and survival. SHISA9 has been shown to play a role in the regulation of FBN1 gene expression, which may make it a potential drug target for SHISA9-mediated diseases.

Another potential drug target for SHISA9 is the PDGF-尾 gene, which encodes a protein that is involved in cell signaling and growth. SHISA9 has been shown to regulate PDGF-尾 gene expression and has been linked to the development of various diseases, including cancer. Therefore, SHISA9 may be a potential drug target for SHISA9-mediated diseases that are caused by the over-expression or deregulation of PDGF-尾 genes.

In addition to these potential drug targets, SHISA9 has also been shown to be involved in the regulation of various cellular processes, including cell adhesion, migration, and invasion. Therefore, SHISA9 may also be a potential drug target for diseases that are caused by the disruption of these processes, such as cancer.

Potential Biomarkers

SHISA9 has the potential to serve as a biomarker for various diseases due to its involvement in the regulation of various cellular processes. One of the potential biomarkers for SHISA9 is the expression of SHISA9 itself. The expression of SHISA9 has been shown to be associated with various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. Therefore, the expression of SHISA9 may be a potential biomarker for these diseases.

Another potential biomarker for SHISA9 is the function of SHISA9-regulated genes. SHISA9 has been shown to regulate the expression of various genes that are involved in cell signaling and growth, including FBN1, PDGF-尾, and various cell adhesion molecules. The function of these genes may be used as potential biomarkers for SHISA9-mediated diseases.

Conclusion

In conclusion, SHISA9 is a gene that encodes a protein located in the ER of eukaryotic cells. Its unique structure and involvement in various cellular processes make it an attractive candidate for drug targeting and biomarker research. The potential drug targets for SHISA9 include the FBN1 gene and the PDGF-尾 gene, as well as the regulation of various cellular processes, including cell adhesion, migration, and invasion. The potential biomarkers for SHISA9 include the expression of SHISA9 itself and the function of SHISA9-regulated genes. Further research is needed to fully understand the potential of SHISA9 as a drug target and biomarker.

Protein Name: Shisa Family Member 9

Functions: Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses (By similarity)

The "SHISA9 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SHISA9 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SHISAL1 | SHISAL2A | SHISAL2B | SHKBP1 | SHLD1 | SHLD2 | SHLD2P1 | SHLD2P3 | SHLD3 | SHMT1 | SHMT2 | SHOC1 | SHOC2 | Short transient receptor potential channel (TrpC) | SHOX | SHOX2 | SHPK | SHPRH | SHQ1 | SHROOM1 | SHROOM2 | SHROOM3 | SHROOM4 | SHTN1 | SI | SIAE | SIAH1 | SIAH2 | SIAH3 | Sialidase | Sialyltransferase | SIDT1 | SIDT2 | SIGIRR | SIGLEC1 | SIGLEC10 | SIGLEC11 | SIGLEC12 | SIGLEC14 | SIGLEC15 | SIGLEC16 | SIGLEC17P | SIGLEC5 | SIGLEC6 | SIGLEC7 | SIGLEC8 | SIGLEC9 | SIGLECL1 | sigma Receptor | SIGMAR1 | Signal peptidase complex | Signal recognition particle | Signal recognition particle receptor | Signal Transducers and Activators of Transcription (STAT) | SIK1 | SIK2 | SIK3 | SIKE1 | SIL1 | SILC1 | SIM1 | SIM2 | SIMC1 | SIN3 complex | SIN3A | SIN3B | SINHCAF | SIPA1 | SIPA1L1 | SIPA1L1-AS1 | SIPA1L2 | SIPA1L3 | SIRPA | SIRPAP1 | SIRPB1 | SIRPB2 | SIRPB3P | SIRPD | SIRPG | SIRPG-AS1 | SIRT1 | SIRT2 | SIRT3 | SIRT4 | SIRT5 | SIRT6 | SIRT7 | SIT1 | SIVA1 | SIX1 | SIX2 | SIX3 | SIX3-AS1 | SIX4 | SIX5 | SIX6 | SKA1 | SKA1 complex | SKA2 | SKA2P1