Target Name: MAP4K1
NCBI ID: G11184
Review Report on MAP4K1 Target / Biomarker Content of Review Report on MAP4K1 Target / Biomarker
MAP4K1
Other Name(s): MEK kinase kinase 1 | M4K1_HUMAN | Mitogen-activated protein kinase kinase kinase kinase 1 | Mitogen-activated protein kinase kinase kinase kinase 1 (isoform 2) | Hematopoietic progenitor kinase | Mitogen-activated protein kinase kinase kinase kinase 1 (isoform 1) | MAP4K1 variant 1 | MAPK/ERK kinase kinase kinase 1 | Hematopoietic progenitor kinase 1 | MEKKK 1 | Mitogen-activated protein kinase kinase kinase kinase 1, transcript variant 1 | hematopoietic progenitor kinase 1 | Mitogen-activated protein kinase kinase kinase kinase 1, transcript variant 2 | mitogen-activated protein kinase kinase kinase kinase 1 | MAP4K1 variant 2 | HPK1

MAP4K1: A Potential Drug Target

MAP4K1 (MeK kinase kinase 1) is a protein that is highly expressed in many tissues and is involved in a variety of cellular processes. It is a key regulator of the MAPK/ERK signaling pathway, which is involved in a wide range of cellular processes, including cell growth, differentiation, and survival.

MAP4K1 is a 21-kDa protein that is expressed in many tissues, including muscle, heart, brain, and pancreas. It is highly expressed in the brain and is one of the most highly expressed proteins in the brain. It is also expressed in other tissues, including the lungs, liver, and heart.

MAP4K1 is involved in a variety of cellular processes, including cell growth, differentiation, and survival. It is a key regulator of the MAPK/ERK signaling pathway, which is involved in a wide range of cellular processes, including cell growth, differentiation, and survival. MAP4K1 is also involved in the regulation of cell adhesion, cell migration, and the regulation of ion channels.

MAP4K1 is a protein that has been identified as a potential drug target. Studies have shown that MAP4K1 is highly expressed in many tissues and that it is involved in a variety of cellular processes. It is also a key regulator of the MAPK/ERK signaling pathway, which is involved in a wide range of cellular processes, including cell growth, differentiation, and survival.

MAP4K1 is a protein that has been shown to be involved in the regulation of cell adhesion, cell migration, and the regulation of ion channels. It is also involved in the regulation of cell growth, differentiation, and survival. These properties make MAP4K1 a potential drug target.

MAP4K1 is a protein that has been shown to be involved in the regulation of cell adhesion, cell migration, and the regulation of ion channels. It is also involved in the regulation of cell growth, differentiation, and survival. These properties make MAP4K1 a potential drug target.

In conclusion, MAP4K1 is a protein that is involved in a variety of cellular processes and has been shown to be a potential drug target. Further research is needed to fully understand the role of MAP4K1 in cellular processes and to develop effective treatments for MAP4K1-related diseases.

Protein Name: Mitogen-activated Protein Kinase Kinase Kinase Kinase 1

Functions: Serine/threonine-protein kinase, which may play a role in the response to environmental stress (PubMed:24362026). Appears to act upstream of the JUN N-terminal pathway (PubMed:8824585). May play a role in hematopoietic lineage decisions and growth regulation (PubMed:8824585, PubMed:24362026). Able to autophosphorylate (PubMed:8824585). Together with CLNK, it enhances CD3-triggered activation of T-cells and subsequent IL2 production (By similarity)

The "MAP4K1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MAP4K1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

MAP4K1-AS1 | MAP4K2 | MAP4K3 | MAP4K3-DT | MAP4K4 | MAP4K5 | MAP6 | MAP6D1 | MAP7 | MAP7D1 | MAP7D2 | MAP7D3 | MAP9 | MAPK1 | MAPK10 | MAPK10-AS1 | MAPK11 | MAPK12 | MAPK13 | MAPK14 | MAPK15 | MAPK1IP1L | MAPK3 | MAPK4 | MAPK6 | MAPK6P2 | MAPK7 | MAPK8 | MAPK8IP1 | MAPK8IP1P2 | MAPK8IP2 | MAPK8IP3 | MAPK9 | MAPKAP1 | MAPKAPK2 | MAPKAPK3 | MAPKAPK5 | MAPKAPK5-AS1 | MAPKBP1 | MAPRE1 | MAPRE1P2 | MAPRE2 | MAPRE3 | MAPT | MAPT-AS1 | MAPT-IT1 | MARCHF1 | MARCHF10 | MARCHF11 | MARCHF11-DT | MARCHF2 | MARCHF3 | MARCHF4 | MARCHF5 | MARCHF6 | MARCHF6-DT | MARCHF7 | MARCHF8 | MARCHF9 | MARCKS | MARCKSL1 | MARCO | MARF1 | MARK1 | MARK2 | MARK2P5 | MARK2P9 | MARK3 | MARK4 | MARS1 | MARS2 | MARVELD1 | MARVELD2 | MARVELD3 | MAS1 | MAS1L | MASP1 | MASP2 | MAST1 | MAST2 | MAST3 | MAST4 | MASTL | MAT1A | MAT2A | MAT2B | MATCAP1 | MATCAP2 | MATK | MATN1 | MATN1-AS1 | MATN2 | MATN3 | MATN4 | MATR3 | Matrix Metalloproteinase (MMP) | MAU2 | MAVS | MAX | MAZ