XAGE5: A Drug Target / Disease Biomarker (G170627)

Target Name: XAGE5

NCBI ID: G170627

XAGE5

XAGE5: A Drug Target / Disease Biomarker

XAGE5 is a protein that is expressed in various tissues throughout the body, including the brain, heart, lungs, and gastrointestinal tract. It is a member of the G-protein-coupled receptor (GPCR) family, which is a large superfamily of transmembrane proteins that play a crucial role in cellular signaling. XAGE5 is characterized by its long extracellular domain, which contains a unique farnesylated cysteine residue that is involved in its stability and functions.

XAGE5 is involved in a wide range of physiological processes in the body, including cell signaling, neurotransmission, and inflammation. It is a key regulator of the neurotransmitter serotonin, which is involved in mood, appetite, and other physiological processes. XAGE5 is also involved in the regulation of pain, anxiety, and inflammation.

Due to its involvement in so many important physiological processes, XAGE5 has been identified as a potential drug target. Researchers are exploring the use of small molecules and other compounds to modulate the activity of XAGE5 and its downstream targets. One of the most promising strategies is the use of biased fragment complementation, a technique that involves the use of small molecules to selectively bind to a protein with a specific function. By using biased fragment complementation, researchers have been able to develop compounds that enhance the activity of XAGE5 and its downstream targets.

In addition to its potential as a drug target, XAGE5 is also a valuable biomarker for the diagnosis and prognosis of various diseases. For example, XAGE5 has been shown to be downregulated in various psychiatric disorders, including depression and anxiety. This suggests that XAGE5 may be a promising target for the development of new treatments for these disorders. Additionally, XAGE5 has also been shown to be involved in the regulation of inflammation, which could make it an attractive target for the development of new treatments for inflammatory diseases.

Overall, XAGE5 is a protein that is involved in a wide range of important physiological processes in the body. Its unique farnesylated cysteine residue and its involvement in the regulation of neurotransmission, pain, anxiety, and inflammation make it a promising target for the development of new drugs and biomarkers. Further research is needed to fully understand the role of XAGE5 in the body and its potential as a drug target.

Protein Name: X Antigen Family Member 5

The "XAGE5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about XAGE5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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