Understanding MTLN: A Protein Target for Cancer and Other Diseases

Target Name: MTLN

NCBI ID: G205251

MTLN

Understanding MTLN: A Protein Target for Cancer and Other Diseases

MTLN (Myostatin) is a protein that is expressed in various tissues throughout the body, including muscle and heart cells. It is a key regulator of muscle growth and function, and has been shown to have a wide range of potential applications in both human and animal disease. As a drug target, MTLN is being targeted for treatment of a variety of conditions, including cancer, neurodegenerative diseases, and muscle-related injuries.

One of the key reasons for the popularity of MTLN as a drug target is its ability to stimulate the production of new muscle cells, as well as the growth of existing muscle fibers. This has the potential to treat a variety of conditions that are characterized by muscle weakness or dysfunction, such as muscle-related injuries, multiple sclerosis, and cancer.

In addition to its ability to stimulate muscle growth and repair, MTLN has also been shown to have a variety of other potential therapeutic effects. For example, it has been shown to have anti-inflammatory properties, and to reduce the expression of genes that are involved in the development of cancer.

MTLN is also a good candidate for a biomarker, which is a substance that is used to diagnose, monitor, or predict the outcome of a disease. Because MTLN is highly expressed in a variety of tissues and is involved in a wide range of cellular processes, it has the potential to serve as a valuable biomarker for a variety of diseases.

One of the challenges in studying MTLN as a drug target is its complex structure and function. MTLN is a large protein that is composed of multiple domains, including an extracellular domain, a transmembrane domain, and an intracellular domain. These domains give MTLN its unique structure and function, and make it difficult to study.

In order to study MTLN more effectively, researchers have developed a variety of techniques to study its structure and function. These techniques include biochemical assays, such as protein-fragment complementation assays, and cell-based assays, such as muscle cell cultures and RNA interference experiments. In addition to these techniques, researchers have also used advanced technologies, such as mass spectrometry and X-ray crystallography, to study the structure and function of MTLN.

Despite the challenges, researchers are making progress in understanding the structure and function of MTLN. They have identified several key regions of the protein that are involved in its function, and have shown that these regions play important roles in regulating muscle growth and repair. They have also developed new assays and techniques for studying MTLN, and have made new discoveries about its structure and function.

In addition to its potential as a drug target and biomarker, MTLN is also of interest as a potential therapeutic agent for a variety of other conditions. For example, MTLN has been shown to have a variety of potential anti-inflammatory effects, and has been shown to reduce the expression of genes that are involved in cancer development. This makes it a potential candidate for a variety of therapeutic applications, including the treatment of multiple sclerosis and cancer.

Overall, MTLN is a protein that has a wide range of potential applications in both human and animal disease. As a drug target and biomarker, it is an promising target for the treatment of a variety of conditions, including cancer, neurodegenerative diseases, and muscle-related injuries. While there are still many challenges to be overcome in studying MTLN, researchers are making progress in understanding its structure and function, and are developing new technologies to study it.

Protein Name: Mitoregulin

Functions: Positively regulates mitochondrial complex assembly and/or stability (By similarity). Increases mitochondrial membrane potential while decreasing mitochondrial reactive oxygen species (PubMed:29949756). Increases mitochondrial respiration rate (PubMed:29949756). Increased mitochondrial respiratory activity promotes myogenic differentiation which facilitates muscle growth and regeneration (By similarity). Increases mitochondrial calcium retention capacity (PubMed:29949756). Plays a role in maintenance of cellular lipid composition through its interaction with cytochrome b5 reductase CYB5R3 which is required for mitochondrial respiratory complex I activity (By similarity). Interacts with the mitochondrial trifunctional enzyme complex (MTE) and enhances fatty acid beta-oxidation (PubMed:32243843). Not required for MTE formation or stability (By similarity). Modulates triglyceride clearance in adipocytes through its role in regulating fatty acid beta-oxidation and lipolysis (PubMed:32243843)

The "MTLN Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MTLN comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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