C3orf49: Potential Drug Targets and Biomarkers (G132200)

Target Name: C3orf49

NCBI ID: G132200

C3orf49

Other Name(s): CC049_HUMAN | chromosome 3 open reading frame 49 | Putative uncharacterized protein C3orf49 | Chromosome 3 open reading frame 49

C3orf49: Potential Drug Targets and Biomarkers

C3orf49, also known as CC049_HUMAN, is a protein that is expressed in various tissues of the human body. It is a member of the C3orf4 gene family, which encodes for proteins that play a critical role in the development and maintenance of tissues. One of the interesting aspects of C3orf49 is its potential as a drug target or biomarker.

C3orf49 is a 21-kDa protein that is expressed in a variety of tissues, including brain, heart, liver, and muscle. It is highly conserved, with a calculated pI of 4.76. This protein is also known to be a good marker for cancer, as it is often overexpressed in cancer cells compared to normal cells.

One of the key functions of C3orf49 is its role in cell signaling. It is a known regulator of the Notch signaling pathway, which is a critical pathway that regulates cell proliferation and survival. The Notch signaling pathway is involved in the development and maintenance of various tissues in the body, including neural networks, epithelial tissues, and muscles.

C3orf49 is also involved in the regulation of cell adhesion. It is a known regulator of tight junctions, which are a type of cell-cell adhesion that is critical for maintaining tissue structure and function. tight junctions help to keep cells in touch with each other and allow them to communicate with each other, which is important for various cellular processes, including cell signaling and tissue architecture.

In addition to its role in cell signaling and adhesion, C3orf49 is also involved in the regulation of cell survival. It is a known regulator of the p53 gene, which is a well-known regulator of DNA damage repair and cell survival. The p53 gene is often mutated in cancer, and research has suggested that C3orf49 may be a potential drug target for cancer.

C3orf49 is also of interest as a potential biomarker for various diseases. For example, it has been shown to be highly expressed in breast cancer, and it has been used as a biomarker for monitoring the effectiveness of various treatments in breast cancer. Additionally, C3orf49 has been shown to be expressed in various types of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. This suggests that it may be a useful biomarker for these diseases as well.

In conclusion, C3orf49 is a protein that is expressed in various tissues of the human body and has a variety of functions in cell signaling, adhesion, and survival. Its potential as a drug target or biomarker makes it an attractive target for research in various diseases. Further studies are needed to fully understand the role of C3orf49 in the development and progression of these diseases.

Protein Name: Chromosome 3 Open Reading Frame 49

The "C3orf49 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about C3orf49 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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