C4orf48: A Potential Drug Target and Biomarker (G401115)

Target Name: C4orf48

NCBI ID: G401115

C4orf48

C4orf48: A Potential Drug Target and Biomarker

Cancer is a leading cause of death worldwide, with over 20 million new cases and 5.5 million deaths in 2020, according to the World Health Organization (WHO). The development of new treatments is a critical aspect of cancer research, and identifying potential drug targets is a major focus. One of the promising targets in cancer research is C4orf48, a gene that has been identified as a potential drug target and biomarker for various diseases, including cancer.

C4orf48 is a gene that encodes a protein known as C4ORF48. The protein is a key regulator of the immune response and has been linked to various diseases, including cancer. Studies have shown that individuals with certain genetic variations in the C4ORF48 gene are at an increased risk of developing cancer. These genetic variations have also been associated with poor prognosis in individuals with cancer.

The potential drug target for C4ORF48 is its role in the regulation of the immune response. The immune response is a critical component of the body's defense against cancer, and studies show that C4ORF48 plays a crucial role in regulating the activation and function of natural killer cells , which are a key part of the immune system. natural killer cells are responsible for detecting and destroying cancer cells, and studies have shown that individuals with certain genetic variations in the C4ORF48 gene have reduced levels of natural killer cells, making them more susceptible to cancer.

Another potential drug target for C4ORF48 is its role in the regulation of cell signaling pathways. The C4ORF48 gene has been shown to be involved in various signaling pathways, including the PI3K/Akt signaling pathway. This pathway is involved in the regulation of cell growth, differentiation, and survival, and has been linked to various diseases, including cancer. Studies have shown that individuals with certain genetic variations in the C4ORF48 gene have altered levels of the PI3K/Akt signaling pathway, which may contribute to the development and progression of cancer.

In addition to its potential drug target and biomarker properties, C4ORF48 has also been shown to be a potential biomarker for various diseases, including cancer. Studies have shown that individuals with certain genetic variations in the C4ORF48 gene have increased levels of cell surface markers, such as the MHC class I molecule, which is a key antigen present on cancer cells. These increased levels of cell surface markers may be used as a biomarker for the diagnosis and monitoring of cancer.

Overall, C4ORF48 is a promising target for cancer research due to its involvement in the regulation of the immune response and cell signaling pathways. Further studies are needed to confirm its potential as a drug target and biomarker, and to develop new treatments for various diseases.

Protein Name: Chromosome 4 Open Reading Frame 48

The "C4orf48 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about C4orf48 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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