Target Name: C4B_2
NCBI ID: G100293534
Review Report on C4B_2 Target / Biomarker Content of Review Report on C4B_2 Target / Biomarker
C4B_2
Other Name(s): Complement C4 gamma chain | Complement component C4Ba | Basic complement C4 | Complement C4-B alpha chain | complement component 4B (Chido blood group), copy 2 | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3 | C4Ba_(HUMAN) | Complement C4 beta chain | C4b-B | Complement component C4Bb | C4d-B | C4Bb_(HUMAN) | C4Ba | CO4B_HUMAN | Complement component 4B (Chido blood group), copy 2 | C4a anaphylatoxin | Complement C4-B

C4B_2: A Potential Drug Target and Biomarker

C4B_2 is a protein that is expressed in the endoplasmic reticulum (ER) and is involved in the regulation of cell signaling pathways, including apoptosis (programmed cell death) and autophagy (cellular degradation). The identification of new drug targets and biomarkers is a critical step in the development of new treatments for various diseases. C4B_2 is a potential drug target and biomarker due to its unique function and its involvement in cellular processes that are associated with a variety of diseases.

Diseases and Their Significance

C4B_2 is involved in the regulation of apoptosis, which is a natural cell death process that helps remove damaged or dysfunctional cells from the body. Abnormalities in apoptosis have been implicated in a wide range of diseases, including neurodegenerative disorders, cancer, and cardiovascular diseases. Therefore, targeting C4B_2 as a drug target has the potential to treat a variety of diseases.

Autophagy is another cellular process that is regulated by C4B_2. It is a process by which cells break down and recycle damaged or unnecessary cellular components, such as proteins, RNA, and vesicles. Abnormalities in autophagy have also been linked to a variety of diseases, including cancer, neurodegenerative disorders, and diseases of the gastrointestinal tract. Therefore, targeting C4B_2 as a drug target has the potential to treat a wide range of diseases.

C4B_2 is also involved in the regulation of cell signaling pathways, including the TGF-β pathway. TGF-β is a cytokine that regulates cellular processes, including cell growth, differentiation, and inflammation. Abnormalities in TGF-β signaling have been implicated in a variety of diseases, including cancer, neurodegenerative disorders, and diseases of the cardiovascular system. Therefore, targeting C4B_2 as a drug target has the potential to treat a wide range of diseases.

C4B_2 is a protein that is expressed in the ER and is involved in the regulation of apoptosis, autophagy, and cell signaling pathways. Its unique function and its involvement in cellular processes that are associated with a variety of diseases make it a potential drug target and biomarker. Further research is needed to fully understand the role of C4B_2 in disease and to identify new treatments for various diseases.

Conclusion

In conclusion, C4B_2 is a protein that is expressed in the ER and is involved in the regulation of apoptosis, autophagy, and cell signaling pathways. Its unique function and its involvement in cellular processes that are associated with a variety of diseases make it a potential drug target and biomarker. Further research is needed to fully understand the role of C4B_2 in disease and to identify new treatments for various diseases.

Protein Name: Complement Component 4B (Chido Blood Group), Copy 2

Functions: Non-enzymatic component of the C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens

The "C4B_2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about C4B_2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

C4orf17 | C4orf19 | C4orf3 | C4orf33 | C4orf36 | C4orf45 | C4orf46 | C4orf46P3 | C4orf47 | C4orf48 | C4orf50 | C4orf51 | C4orf54 | C5 | C5-OT1 | C5AR1 | C5AR2 | C5orf15 | C5orf22 | C5orf24 | C5orf34 | C5orf46 | C5orf47 | C5orf52 | C5orf58 | C5orf60 | C5orf63 | C5orf64 | C5orf64-AS1 | C5orf67 | C6 | C6orf118 | C6orf120 | C6orf132 | C6orf136 | C6orf141 | C6orf15 | C6orf163 | C6orf226 | C6orf47 | C6orf52 | C6orf58 | C6orf62 | C6orf89 | C7 | C7orf13 | C7orf25 | C7orf31 | C7orf33 | C7orf50 | C7orf57 | C8A | C8B | C8G | C8orf33 | C8orf34 | C8orf34-AS1 | C8orf44 | C8orf48 | C8orf58 | C8orf74 | C8orf76 | C8orf82 | C8orf88 | C8orf89 | C9 | C9orf131 | C9orf152 | C9orf153 | C9orf163 | C9orf24 | C9orf40 | C9orf43 | C9orf47 | C9orf50 | C9orf57 | C9orf64 | C9orf72 | C9orf78 | C9orf78P2 | C9orf85 | CA1 | CA10 | CA11 | CA12 | CA13 | CA14 | CA15P1 | CA2 | CA3 | CA3-AS1 | CA4 | CA5A | CA5B | CA5BP1 | CA6 | CA7 | CA8 | CA9 | CAAP1