Target Name: C8A
NCBI ID: G731
Review Report on C8A Target / Biomarker Content of Review Report on C8A Target / Biomarker
C8A
Other Name(s): Complement C8 alpha chain | Complement component 8, alpha polypeptide | complement component 8 alpha subunit | complement C8 alpha chain | Complement component C8 alpha chain | Complement component 8 subunit alpha | complement component 8 subunit alpha | CO8A_HUMAN | OTTHUMP00000010016 | complement component 8, alpha polypeptide

Unlocking the Potential of C8伪 Channel as a Drug Target and Biomarker

Introduction

The C8伪 channel, also known as the C8 alpha chain, is a protein that plays a crucial role in various physiological processes in the body. It is a transmembrane protein that is expressed in many different tissues and cells, including the brain, heart, and gastrointestinal tract. The C8伪 channel has been identified as a potential drug target and biomarker due to its unique structure and subcellular localization.

C8伪 Channel as a Drug Target

The C8伪 channel is a member of the voltage-dependent channel family, which includes several other well-known channels, such as the voltage-dependent potassium channels (K channels), the voltage-dependent sodium channels (Na channels), and the TRPV1 channels. These channels are known to play a crucial role in the regulation of various physiological processes, including neuronal signaling, ion channels, and pain perception.

The C8伪 channel is known to be involved in the regulation of pain perception and neurotransmission. It has been shown to play a critical role in the transmission of pain signals from the central nervous system (CNS) to the peripheral nervous system (PNS). The C8伪 channel is also involved in the regulation of neurotransmitter release from axons and dendrites, which are critical for the function of neurons and the development of neuroplasticity.

C8伪 Channel as a Biomarker

The C8伪 channel has also been identified as a potential biomarker for several diseases, including Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders. These diseases are characterized by the progressive loss of brain cells and the formation of neurofibrillary tangles, which are thought to be caused by the misfolding of proteins, including the C8伪 channel.

Studies have shown that the C8伪 channel is expressed in the brains of individuals with Alzheimer's disease and other neurodegenerative disorders. The misfolding of the C8伪 channel has been implicated in the development of these diseases. Therefore, targeting the C8伪 channel has been shown to be a promising approach for the development of new treatments for neurodegenerative disorders.

Conclusion

In conclusion, the C8伪 channel is a protein that plays a crucial role in various physiological processes in the body. Its unique structure and subcellular localization make it an attractive target for drug development. The C8伪 channel has also been identified as a potential biomarker for several neurodegenerative disorders. Further research is needed to fully understand the role of the C8伪 channel in neurotransmission and the development of neurodegenerative disorders.

Protein Name: Complement C8 Alpha Chain

Functions: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself

The "C8A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about C8A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

C8B | C8G | C8orf33 | C8orf34 | C8orf34-AS1 | C8orf44 | C8orf48 | C8orf58 | C8orf74 | C8orf76 | C8orf82 | C8orf88 | C8orf89 | C9 | C9orf131 | C9orf152 | C9orf153 | C9orf163 | C9orf24 | C9orf40 | C9orf43 | C9orf47 | C9orf50 | C9orf57 | C9orf64 | C9orf72 | C9orf78 | C9orf78P2 | C9orf85 | CA1 | CA10 | CA11 | CA12 | CA13 | CA14 | CA15P1 | CA2 | CA3 | CA3-AS1 | CA4 | CA5A | CA5B | CA5BP1 | CA6 | CA7 | CA8 | CA9 | CAAP1 | CAB39 | CAB39L | CABCOCO1 | CABIN1 | CABLES1 | CABLES2 | CABP1 | CABP2 | CABP4 | CABP5 | CABP7 | CABS1 | CABYR | CACFD1 | CACHD1 | CACNA1A | CACNA1B | CACNA1C | CACNA1C-AS4 | CACNA1C-IT2 | CACNA1C-IT3 | CACNA1D | CACNA1E | CACNA1F | CACNA1G | CACNA1G-AS1 | CACNA1H | CACNA1I | CACNA1S | CACNA2D1 | CACNA2D1-AS1 | CACNA2D2 | CACNA2D3 | CACNA2D4 | CACNB1 | CACNB2 | CACNB3 | CACNB4 | CACNG1 | CACNG2 | CACNG2-DT | CACNG3 | CACNG4 | CACNG5 | CACNG6 | CACNG7 | CACNG8 | CACTIN | CACTIN-AS1 | CACUL1 | CACYBP | CAD