CCDC89: A Promising Drug Target and Biomarker for diseases (G220388)

Target Name: CCDC89

NCBI ID: G220388

CCDC89

CCDC89: A Promising Drug Target and Biomarker for diseases

The protein CCDC89, also known as Coiled-coil domain-containing protein 89, is a member of the coat protein family that is widely expressed in various cell types of the human body. It plays a critical role in cell signaling, tissue structure, and embryonic development. The identification and characterization of CCDC89 as a potential drug target and biomarker have generated significant interest in the field of molecular medicine. In this article, we will provide an overview of CCDC89, its functions, potential drug targets, and its potential as a biomarker for diseases.

Function and localization

CDC89 is a 25kDa protein that is composed of 116 amino acid residues. It is characterized by a long N-terminal coiled-coil that is responsible for its unique physical and functional properties. The N-terminus of CCDC89 contains a conserved region that is involved in its interactions with other proteins. The C-terminus of CCDC89 contains a unique farnesylated cysteine residue that is involved in its stability and functions as a protein domains.

CDC89 is highly expressed in various tissues, including brain, heart, liver, and muscle. It is also expressed in the plasma and urine, which suggests its potential as a biomarker for diseases. The localization of CCDC89 in various tissues is also of interest, as it may play a role in the development and progression of diseases.

Potential drug targets

The unique features of CCDC89 make it an attractive drug target. One of the most promising aspects of CCDC89 is its involvement in cell signaling. CCDC89 has been shown to play a role in the regulation of cell signaling pathways, including the Wnt/FGF signaling pathway. This pathway is involved in the development and maintenance of tissues and organs, and is a key factor in the development of many diseases, including cancer.

In addition to its involvement in cell signaling, CCDC89 has also been shown to play a role in the regulation of cell adhesion. CCDC89 is a critical protein for the regulation of cell adhesion, which is involved in the development and maintenance of tissues and organs. The disruption of cell adhesion has been implicated in the development of many diseases, including cancer, neurodegenerative diseases, and developmental disorders.

CDC89 has also been shown to play a role in the regulation of the cytoskeleton. The cytoskeleton is responsible for the structure and function of cells, and is involved in many cellular processes, including cell division, migration, and organization. The regulation of the cytoskeleton is critical for the development and maintenance of tissues and organs, and is a key factor in the development of many diseases.

Potential biomarkers

The potential use of CCDC89 as a biomarker for diseases has generated significant interest in the field of molecular medicine. CCDC89 has been shown to be involved in the development and progression of many diseases, including cancer, neurodegenerative diseases, and developmental disorders. Its involvement in these diseases makes it an attractive potential biomarker for these conditions.

One of the key advantages of CCDC89 as a biomarker is its stability and persistence in various tissues. CCDC89 is highly stable in the brain, heart, and liver, and has been shown to persist for long periods of time. This stability is of interest, as it suggests that CCDC89 may be a reliable biomarker for diseases that involve long-term persistence in the body.

Another advantage of CCDC89 as a biomarker is its ability to be targeted by small molecules. The farnesylated cysteine residue on the C-terminus of CCDC89 makes it a target for small molecules that are able to modulate its stability and functions. This has led to the development of CCDC89-targeted drugs that have been shown to be effective in treating diseases.

Conclusion

In conclusion, CCDC89 is a protein that has significant potential as a drug target and biomarker for diseases. Its unique features, including its coiled-coil structure and its involvement in cell signaling pathways, cell adhesion, and cytoskeleton regulation, make it an attractive target for small molecules. Its stability and persistence in various tissues and its ability to be targeted by small molecules make it an attractive potential biomarker for diseases. Further research is needed to fully understand the functions and potential of CCDC89 as a drug target and biomarker for diseases.

Protein Name: Coiled-coil Domain Containing 89

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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