Target Name: CCHCR1
NCBI ID: G54535
Review Report on CCHCR1 Target / Biomarker Content of Review Report on CCHCR1 Target / Biomarker
CCHCR1
Other Name(s): Chromosome 6 open reading frame 18 | Coiled-coil alpha-helical rod protein 1, transcript variant 3 | CCHCR1 variant 1 | StAR-binding protein | OTTHUMP00000029150 | Coiled-coil alpha-helical rod protein 1 (isoform 3) | CCHCR1 variant 2 | Alpha helical coiled-coil rod protein | OTTHUMP00000165081 | HCR | OTTHUMP00000165085 | Coiled-coil alpha-helical rod protein 1, transcript variant 2 | Coiled-coil alpha-helical rod protein 1 (isoform 1) | OTTHUMP00000165080 | Pg8 | Putative gene 8 protein | Coiled-coil alpha-helical rod protein 1 | OTTHUMP000001650858 | Alpha-helical coiled-coil rod protein | MGC126372 | SBP | C6orf18 | coiled-coil alpha-helical rod protein 1 | CCHCR1 variant 3 | Coiled-coil alpha-helical rod protein 1, transcript variant 1 | MGC126371 | pg8 | Coiled-coil alpha-helical rod protein 1 (isoform 2) | CCHCR_HUMAN | HCR (a-helix coiled-coil rod homologue) | putative gene 8 protein | alpha-helical coiled-coil rod protein

CCHCR1: A Potential Drug Target and Biomarker

Thechromosomal complex heat shock factor 1 (CCHCR1) is a protein that plays a critical role in the regulation of gene expression and DNA replication in eukaryotic cells. It is highly conserved across various species, and its function has been extensively studied. CCHCR1 has been implicated in various cellular processes, including DNA replication, transcription, and stress responses. Its role in these processes makes it an attractive drug target and a potential biomarker for various diseases.

Drug Target Potential

The CCHCR1 protein is a target for small molecules, such as drugs that can modulate its activity. CCHCR1 has been shown to interact with various small molecules, including inhibitors, modulators, and antagonists. These interactions suggest that CCHCR1 can be a drug target with potential for treating various diseases.

One of the known drug targets for CCHCR1 is the inhibitor of DNA-protein binding, pyridostigmine. Pyridostigmine is a potent inhibitor of CCHCR1, and it has been shown to inhibit the activity of CCHCR1 in cell culture and in animal models of disease. The results suggest that pyridostigmine could be a useful agent for treating diseases that are characterized by the over-expression of CCHCR1.

Biomarker Potential

CCHCR1 is also an attractive biomarker for various diseases due to its unique expression patterns. High levels of CCHCR1 have been observed in various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. These studies suggest that CCHCR1 may serve as a potential biomarker for these diseases and could be used for diagnostic purposes.

One of the diseases that has been identified as a potential target for CCHCR1 is neurodegenerative diseases, such as Alzheimer's disease. Studies have shown that the expression of CCHCR1 is increased in the brains of individuals with Alzheimer's disease, and that it is associated with the development and progression of the disease. Therefore, CCHCR1 has been identified as a potential biomarker for Alzheimer's disease and could be used for diagnostic purposes.

Another potential disease that could benefit from CCHCR1 targeting is cancer. The over-expression of CCHCR1 has been observed in various types of cancer, including breast, lung, and ovarian cancer. Therefore, CCHCR1 has been identified as a potential biomarker for cancer and could be used for diagnostic purposes.

Conclusion

In conclusion, CCHCR1 is a protein that has the potential to serve as a drug target and biomarker for various diseases. Its unique function in regulating gene expression and DNA replication makes it an attractive target for small molecules. The inhibitor of DNA-protein binding, pyridostigmine, has already been shown to be effective in modulating CCHCR1 activity, and its expression patterns in various diseases make it a potential biomarker. Further research is needed to fully understand the potential of CCHCR1 as a drug target and biomarker for various diseases.

Protein Name: Coiled-coil Alpha-helical Rod Protein 1

Functions: May be a regulator of keratinocyte proliferation or differentiation

The "CCHCR1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CCHCR1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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