Heat-Induced Protein HSPA4L: A Potential Drug Target (G22824)

Target Name: HSPA4L

NCBI ID: G22824

HSPA4L

Heat-Induced Protein HSPA4L: A Potential Drug Target

Heat shock 70 kDa (HSPA4L) protein is a heat-induced protein that is expressed in various cell types in the body. HSPA4L is a member of the HSPA family, which is known for their ability to withstand high levels of thermal stress. HSPA4L is a unique protein as it is expressed in the cytoplasm of the cells, whereas most heat-induced proteins are expressed in the nucleus.

HSPA4L is a protein that plays a crucial role in the regulation of cellular processes. It is involved in the cell cycle, cell growth, and DNA replication. HSPA4L is also involved in the regulation of cell adhesion, migration and invasion.

In addition to its role in cell biology, HSPA4L is also a potential drug target. HSPA4L has been shown to be a potential biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

One of the key reasons for HSPA4L's potential as a drug target is its unique expression pattern. HSPA4L is primarily expressed in the cytoplasm, which makes it difficult to target within this cell compartment. Additionally, HSPA4L is a large protein with a calculated molecular mass of 41.1 kDa, which makes it difficult to produce and purify.

However, researchers have been able to develop small interfering RNA (siRNA) based therapies that target HSPA4L. These therapies have been shown to reduce the expression of HSPA4L and increase the levels of other proteins involved in cell cycle and survival.

Another approach to targeting HSPA4L is through the use of monoclonal antibodies (mAbs). HSPA4L is a protein that is expressed in various cell types, making it difficult to target with small molecules. However, mAbs have been developed that are specific for HSPA4L and can be used to block its expression in cancer cells.

In conclusion, HSPA4L is a protein that has the potential to be a drug target. Its unique expression pattern and large size make it difficult to target, but researchers have been able to develop small interfering RNA and monoclonal antibodies that can target HSPA4L. Further research is needed to fully understand the potential of HSPA4L as a drug target and to develop effective therapies for the treatment of diseases associated with its over-expression.

Protein Name: Heat Shock Protein Family A (Hsp70) Member 4 Like

Functions: Possesses chaperone activity in vitro where it inhibits aggregation of citrate synthase

The "HSPA4L Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HSPA4L comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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