Target Name: HSPB11
NCBI ID: G51668
Review Report on HSPB11 Target / Biomarker Content of Review Report on HSPB11 Target / Biomarker
HSPB11
Other Name(s): Heat shock protein beta-11 | heat shock protein beta-11 | Intraflagellar transport protein 25 homolog | heat shock protein family B (small) member 11 | IFT25_HUMAN | C1orf41 | HSPB11 variant 1 | placental protein 25 | intraflagellar transport 25 homolog | Intraflagellar transport protein 25 homolog (isoform a) | Intraflagellar transport 25 homolog | HSPCO34 | IFT25 | PP25 | Hspb11 | Placental protein 25 | FAP232 | heat shock protein family B (small), member 11 | CFAP232 | Heat shock protein family B (small) member 11, transcript variant 1

Heat Shock Protein HSP-11: Potential Drug Target and Biomarker

Heat shock protein (HSP)尾-11 is a protein that is expressed in a variety of cell types and is involved in the regulation of various cellular processes. HSP尾-11 has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

HSP尾-11 is a member of the HSP family, which includes a variety of proteins that are involved in the regulation of protein synthesis and quality control. HSP尾-11 is a 14kDa protein that is expressed in a variety of tissues, including muscle, heart, brain, and cancer cells. It is highly conserved and has a similar structure to other HSP尾 proteins.

HSP尾-11 plays a role in the regulation of various cellular processes, including cell growth, apoptosis, and DNA damage repair. It is involved in the formation of stress-protein bonds, which are important for the regulation of cellular stress response. HSP尾-11 is also involved in the regulation of protein synthesis and stability, as well as in the regulation of cellular signaling pathways.

As a potential drug target, HSP尾-11 is being studied for its ability to modulate cellular behavior and prevent the development of various diseases. For example, HSP尾-11 has been shown to play a role in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. Studies have shown that HSP尾-11 levels are decreased in the brains of individuals with these conditions, and that inhibition of HSP尾-11 has been shown to protect against neurodegeneration.

HSP尾-11 has also been shown to be involved in the development of cancer. Many studies have shown that HSP尾-11 is expressed in various types of cancer, and that it is involved in the regulation of cellular processes that are important for cancer growth. In addition, HSP尾-11 has been shown to play a role in the regulation of the immune response, and is involved in the development of autoimmune diseases.

Despite the potential benefits of HSP尾-11 as a drug target, there are also concerns about its potential drawbacks. For example, HSP尾-11 has been shown to play a role in the regulation of cellular processes that are important for the development and maintenance of cancer, and it is possible that inhibition of HSP尾-11 could have unintended consequences. Additionally, the regulation of HSP尾-11 is complex and it is not clear how the levels of HSP尾-11 will be regulated by a drug.

In conclusion, HSP尾-11 is a protein that is involved in the regulation of various cellular processes and has been identified as a potential drug target and biomarker for a variety of diseases. Further research is needed to fully understand the role of HSP尾-11 in cellular processes and its potential as a drug.

Protein Name: Heat Shock Protein Family B (small) Member 11

Functions: Component of the IFT complex B required for sonic hedgehog/SHH signaling. May mediate transport of SHH components: required for the export of SMO and PTCH1 receptors out of the cilium and the accumulation of GLI2 at the ciliary tip in response to activation of the SHH pathway, suggesting it is involved in the dynamic transport of SHH signaling molecules within the cilium. Not required for ciliary assembly. Its role in intraflagellar transport is mainly seen in tissues rich in ciliated cells such as kidney and testis. Essential for male fertility, spermiogenesis and sperm flagella formation. Plays a role in the early development of the kidney. May be involved in the regulation of ureteric bud initiation (By similarity)

The "HSPB11 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HSPB11 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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