HTR5A-AS1: A Potential Drug Target and Biomarker (G100128264)
HTR5A-AS1: A Potential Drug Target and Biomarker
Human tissue runtime (HTR5A) is a gene that encodes a protein known as heat shock protein 5A (HSP5A). HSP5A is a cytoplasmic protein that is expressed in a variety of cell types and is involved in a variety of cellular processes, including stress response, DNA repair, and cell signaling. HTR5A has also been implicated in a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.
One of the potential drug targets for HTR5A is the use of small molecules, such as drugs that bind to HSP5A and prevent it from interacting with its downstream adaptor protein, HSP70. This can lead to the inhibition of HSP5A-mediated cellular processes and the inhibition of the formation of HSP5A-proteins, including stress-induced protein misfolding and aggregation.
Another potential drug target for HTR5A is the use of antibodies that specifically bind to HSP5A and target its juxtamolecular region. This can lead to the inhibition of HSP5A-mediated cellular processes, such as protein-protein interactions, and the formation of aggregates.
In addition to its potential as a drug target, HTR5A has also been identified as a potential biomarker for a number of diseases. For example, HSP5A has been shown to be overexpressed in a variety of cancer types and has been used as a biomarker for the diagnosis and prognosis of cancer.
HTR5A has also been shown to be involved in a number of cellular processes that are important for the development and progression of neurodegenerative diseases. For example, HSP5A has been shown to be involved in the formation of neurofibrillary tangles, which are a hallmark of neurodegenerative diseases, and has been shown to play a role in the regulation of neurotransmitter release.
In addition to its potential role in neurodegenerative diseases, HTR5A has also been implicated in the development and progression of autoimmune disorders. For example, HSP5A has been shown to be involved in the regulation of T cell function and has been implicated in the development of autoimmune diseases.
Overall, HTR5A is a protein that has a number of potential drug targets and may be a useful biomarker for a variety of diseases. Further research is needed to fully understand the role of HTR5A in cellular processes and to develop effective treatments for the prevention and treatment of diseases associated with HTR5A.
Protein Name: HTR5A Antisense RNA 1
More Common Targets
HTR5BP | HTR6 | HTR7 | HTR7P1 | HTRA1 | HTRA2 | HTRA3 | HTRA4 | HTT | HTT-AS | HULC | Human chorionic gonadotropin | HUNK | HUS1 | HUS1B | HUWE1 | HVCN1 | HYAL1 | HYAL2 | HYAL3 | HYAL4 | HYAL6P | Hyaluronidase | HYCC1 | HYCC2 | HYDIN | HYI | HYKK | HYLS1 | HYMAI | HYOU1 | HYPK | Hypoxia inducible factor (HIF) | Hypoxia-Inducible Factor Prolyl Hydroxylase | I-kappa-B-kinase (IKK) complex | IAH1 | IAPP | IARS1 | IARS2 | IATPR | IBA57 | IBA57-DT | IBSP | IBTK | ICA1 | ICA1L | ICAM1 | ICAM2 | ICAM3 | ICAM4 | ICAM5 | ICE1 | ICE2 | ICMT | ICMT-DT | ICOS | ICOSLG | ID1 | ID2 | ID2-AS1 | ID2B | ID3 | ID4 | IDE | IDH1 | IDH1-AS1 | IDH2 | IDH2-DT | IDH3A | IDH3B | IDH3G | IDI1 | IDI2 | IDI2-AS1 | IDNK | IDO1 | IDO2 | IDS | IDSP1 | IDUA | IER2 | IER3 | IER3-AS1 | IER3IP1 | IER5 | IER5L | IER5L-AS1 | IFFO1 | IFFO2 | IFI16 | IFI27 | IFI27L1 | IFI27L2 | IFI30 | IFI35 | IFI44 | IFI44L | IFI6 | IFIH1 | IFIT1