HTR2C Receptor: A Potential Drug Target for Psychiatric Disorders

Target Name: HTR2C

NCBI ID: G3358

HTR2C

HTR2C Receptor: A Potential Drug Target for Psychiatric Disorders

The HTR2C receptor, also known as 5-HT2C receptor, is a G protein-coupled receptor located on the surface of various cell types in the body. This receptor is involved in the signaling of various neurotransmitters, including serotonin, dopamine, and neurotensin. It is a potential drug target and has been identified as a biomarker for various psychiatric and neurological disorders.

The HTR2C receptor is a member of the 5-HT receptor family, which includes four different subtypes: HTR1A, HTR1B, HTR2A, and HTR2C. The HTR2C receptor is one of the most well-studied members of this family, and its function in the body is still being fully understood.

The HTR2C receptor is expressed in various tissues and cell types, including the brain, pancreas, and gastrointestinal tract. It is primarily expressed in the brain and is involved in the regulation of various brain functions, including mood, anxiety, and pain perception.

The HTR2C receptor is involved in the regulation of serotonin, which is a neurotransmitter that plays a crucial role in the brain and body. Serotonin regulates various physiological processes, including mood, appetite, and sleep. It is also involved in the regulation of pain perception and anxiety.

The HTR2C receptor is involved in the regulation of dopamine, which is another neurotransmitter that plays a critical role in the brain. Dopamine is involved in the regulation of movement, emotion, and motivation.

The HTR2C receptor is also involved in the regulation of neurotensin, which is a hormone that regulates various physiological processes in the body. Neurotensin is involved in the regulation of blood pressure, bone density, and inflammation.

The HTR2C receptor is a potential drug target because of its involvement in the regulation of various neurotransmitters. Drugs that block the HTR2C receptor have been shown to be effective in treating various psychiatric and neurological disorders, including depression, anxiety, and psychosis.

In addition to its involvement in neurotransmitter regulation, the HTR2C receptor is also involved in the regulation of ion channels in cells. This suggests that it may play a role in the regulation of electrical activity in the brain and body.

The HTR2C receptor is also involved in the regulation of pain perception. Studies have shown that the HTR2C receptor is involved in the regulation of pain perception and that blockers of this receptor may be effective in treating chronic pain.

The HTR2C receptor is also a potential biomarker for various psychiatric and neurological disorders. Studies have shown that the HTR2C receptor is involved in the regulation of various psychiatric disorders, including depression, anxiety, and psychosis. This suggests that blockers of this receptor may be effective in treating these disorders.

In conclusion, the HTR2C receptor is a G protein-coupled receptor that is involved in the regulation of various neurotransmitters, including serotonin, dopamine, and neurotensin. It is a potential drug target and has been identified as a biomarker for various psychiatric and neurological disorders. Further research is needed to fully understand the function of this receptor and its potential as a drug target.

Protein Name: 5-hydroxytryptamine Receptor 2C

Functions: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca(2+) ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone. Plays a role in the regulation of appetite and eating behavior, responses to anxiogenic stimuli and stress. Plays a role in insulin sensitivity and glucose homeostasis

The "HTR2C Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HTR2C comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets