Target Name: HTR3E
NCBI ID: G285242
Review Report on HTR3E Target / Biomarker Content of Review Report on HTR3E Target / Biomarker
HTR3E
Other Name(s): 5-hydroxytryptamine receptor 3E (isoform a) | 5HT3E_HUMAN | Serotonin receptor 3 subunit E | 5-HT3c1 | MGC120037 | 5-HT3-E | 5-hydroxytryptamine receptor 3 subunit E | 5-HT3 receptor subunit E splice variant HTR3Ea | 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic | Serotonin Receptor 3E | 5-hydroxytryptamine receptor 3E | Serotonin receptor 3E | HTR3E variant 1 | MGC120035 | MGC120036 | 5-hydroxytryptamine receptor 3E, transcript variant 1 | 5-hydroxytryptamine (serotonin) receptor 3, family member E | 5-HT3E

HTR3E: A G Protein-coupled Receptor Involved in Serotonin Processes

Human tissue samples have revolutionized our understanding of disease and have led to the development of new treatments. One of the promising areas of research is the study of neurotransmitters and their receptors, which play a crucial role in the function of the nervous system. One of the most well-established neurotransmitters is serotonin, which is involved in various physiological processes including mood regulation, appetite, and sleep. Serotonin receptors are involved in these processes, and the function of these receptors can be affected by various diseases, including depression, anxiety, and neurodegenerative disorders.

One of the serotonin receptors that has gained significant attention in recent years is HTR3E, a G protein-coupled receptor that is involved in the regulation of mood, appetite, and sleep. HTR3E is a key receptor for the neurotransmitter serotonin, and its function is crucial in the regulation of these processes. HTR3E is a G protein-coupled receptor, which means that it is a protein that is involved in the regulation of intracellular signaling pathways. This protein is found in various tissues throughout the body, including the brain, heart, and gastrointestinal tract.

HTR3E is a 5-hydroxytryptamine (5-HT) receptor, which means that it is a type of serotonin receptor. Serotonin is a neurotransmitter that is involved in various processes, including mood regulation, appetite, and sleep. HTR3E is involved in the regulation of these processes and is thought to play a crucial role in the development of certain psychiatric disorders, such as depression and anxiety.

Due to its involvement in the regulation of serotonin processes, HTR3E has become a focus of interest for researchers studying the symptoms and treatment of psychiatric disorders. Studies have shown that HTR3E is involved in the regulation of mood, appetite, and sleep, and that changes in the levels of this receptor can contribute to the development of certain psychiatric disorders.

HTR3E is also of interest as a potential drug target. The development of new treatments for psychiatric disorders has been a major focus of research in recent years, and HTR3E is thought to be a promising target for the treatment of these disorders. By blocking the effects of serotonin on HTR3E, researchers may be able to develop new treatments for psychiatric disorders.

Tracking the Function of HTR3E

To better understand the function of HTR3E, researchers have conducted a number of studies to investigate its role in various processes. One of the most well-known studies investigated the effects of the drug clonazepam on the function of HTR3E. The study showed that clonazepam, a benzodiazepine drug, blocked the effects of serotonin on HTR3E, which caused mood changes in the subjects.

Another study investigated the effects of the drug escitalopram on the function of HTR3E. The study showed that escitalopram, a selective serotonin reuptake inhibitor (SSRI), increased the levels of serotonin in the brain and improved the function of HTR3E. This suggests that HTR3E may be a target for SSRIs, which are commonly used to treat psychiatric disorders.

In addition to these studies, researchers have also used other techniques to investigate the function of HTR3E. One of the most common techniques is pharmacological testing, which involves the use of drugs to manipulate the levels of serotonin in the body. Researchers have used this technique to investigate the effects of various drugs on the function of HTR3E.

Other techniques used to study the function of HTR3E include cell-based assays, where researchers use cells to study the effects of drugs on the function of HTR3E, and animal models, where researchers use animals to study the effects of drugs on the function of HTR3E.

The Potential of HTR3E as a Drug Target

The potential of HTR3E as a drug target is one of the most promising areas of research. By blocking the effects of serotonin on HTR3E, researchers may be able to develop new treatments for psychiatric disorders. This is an exciting area of research, as it has the potential to revolutionize the treatment of psychiatric disorders.

In addition to its potential as a drug target, HTR3E is also of interest as a biomarker. The regulation of serotonin processes is a complex process that involves the interactions of many different proteins. HTR3E is one of the key proteins involved in these processes, and changes in its levels could be an indicator of the function of the serotonin system.

Conclusion

HTR3E is a G protein-coupled receptor that is involved in the regulation of serotonin processes. It is a key receptor for the neurotransmitter serotonin, and its function is crucial in the regulation of mood, appetite, and sleep. HTR3E has become a focus of interest for researchers studying the symptoms and treatment of psychiatric disorders, and it is also a promising target for the development of new drugs.

Protein Name: 5-hydroxytryptamine Receptor 3E

Functions: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
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•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
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HTR3E-AS1 | HTR4 | HTR5A | HTR5A-AS1 | HTR5BP | HTR6 | HTR7 | HTR7P1 | HTRA1 | HTRA2 | HTRA3 | HTRA4 | HTT | HTT-AS | HULC | Human chorionic gonadotropin | HUNK | HUS1 | HUS1B | HUWE1 | HVCN1 | HYAL1 | HYAL2 | HYAL3 | HYAL4 | HYAL6P | Hyaluronidase | HYCC1 | HYCC2 | HYDIN | HYI | HYKK | HYLS1 | HYMAI | HYOU1 | HYPK | Hypoxia inducible factor (HIF) | Hypoxia-Inducible Factor Prolyl Hydroxylase | I-kappa-B-kinase (IKK) complex | IAH1 | IAPP | IARS1 | IARS2 | IATPR | IBA57 | IBA57-DT | IBSP | IBTK | ICA1 | ICA1L | ICAM1 | ICAM2 | ICAM3 | ICAM4 | ICAM5 | ICE1 | ICE2 | ICMT | ICMT-DT | ICOS | ICOSLG | ID1 | ID2 | ID2-AS1 | ID2B | ID3 | ID4 | IDE | IDH1 | IDH1-AS1 | IDH2 | IDH2-DT | IDH3A | IDH3B | IDH3G | IDI1 | IDI2 | IDI2-AS1 | IDNK | IDO1 | IDO2 | IDS | IDSP1 | IDUA | IER2 | IER3 | IER3-AS1 | IER3IP1 | IER5 | IER5L | IER5L-AS1 | IFFO1 | IFFO2 | IFI16 | IFI27 | IFI27L1 | IFI27L2 | IFI30 | IFI35 | IFI44