HTR4: A G Protein-Coupled Receptor and Potential Drug Target (G3360)

Target Name: HTR4

NCBI ID: G3360

HTR4

HTR4: A G Protein-Coupled Receptor and Potential Drug Target

HTR4, also known as 5-hydroxytryptamine receptor 4, is a G protein-coupled receptor located on the surface of various tissues in the body. This receptor is involved in the regulation of various physiological processes, including mood, appetite, and sleep. It is also potential drug target and biomarker.

HTR4 is a member of the G protein-coupled receptor family, which is a large superfamily of transmembrane proteins that play a fundamental role in cellular signaling. G protein-coupled receptors are involved in the regulation of a wide range of physiological processes, including sensory perception, neurotransmitter signaling, and hormone signaling.

HTR4 is a TrkA subtype of G protein-coupled receptor, which is characterized by the presence of a TrkA伪 subunit and a TrkB尾 subunit. TrkA subunits are involved in the regulation of G protein-coupled receptor function, while TrkB subunits are involved in the regulation of intracellular signaling pathways.

HTR4 is involved in the regulation of various physiological processes, including mood, appetite, and sleep. For example, HTR4 is involved in the regulation of food intake and satiety. HTR4 signaling has been implicated in the development and maintenance of obesity, as well as the regulation of appetite and body weight.

HTR4 is also involved in the regulation of mood and sleep. It is known to play a role in the regulation of emotional behavior, including anxiety and depression. HTR4 signaling has also been implicated in the regulation of sleep-wake cycles and the control of sleepout.

In addition to its involvement in the regulation of physiological processes, HTR4 is also a potential drug target and biomarker. For example, HTR4 has been targeted by several drug developers for the treatment of various psychiatric and neurological disorders, including depression, anxiety, and sleep disorders.

HTR4 is also a potential biomarker for certain diseases, such as cancer. The expression of HTR4 has been observed in various types of cancer, including breast, lung, and colorectal cancer. This suggests that HTR4 may be a useful biomarker for the diagnosis and prognosis of certain types of cancer.

In conclusion, HTR4 is a G protein-coupled receptor that is involved in the regulation of various physiological processes in the body. It is also a potential drug target and biomarker for the treatment of various psychiatric and neurological disorders, as well as cancer. Further research is needed to fully understand the role of HTR4 in the regulation of physiological processes and its potential as a drug target and biomarker.

Protein Name: 5-hydroxytryptamine Receptor 4

Functions: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase

The "HTR4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HTR4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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