KIFAP3: A Potential Drug Target and Biomarker (G22920)

Target Name: KIFAP3

NCBI ID: G22920

KIFAP3

KIFAP3: A Potential Drug Target and Biomarker

Kappa-casein (KAP3) is a protein that is expressed in various tissues and cells throughout the body. It is a member of the kappa-casein family, which is characterized by the presence of a variable region of the protein that is responsible for its unique structure and function. KAP3 is expressed in a variety of tissues, including the brain, heart, kidneys, and pancreas, and is involved in a wide range of physiological processes.

One of the unique features of KAP3 is its ability to interact with other proteins, particularly with the protein known as transthyretin (TTR). TTR is a protein that is synthesized in the liver and is responsible for transporting dietary cholesterol to the bloodstream. KAP3 has been shown to interact with TTR and can modulate its function.

This interaction between KAP3 and TTR raises the possibility that KAP3 could be a drug target. By inhibiting the activity of TTR, researchers may be able to reduce the levels of cholesterol in the bloodstream, which can improve cardiovascular health and reduce the risk of heart disease.

In addition to its potential as a drug target, KAP3 has also been shown to be a potential biomarker for a variety of diseases. For example, researchers have used KAP3 to diagnose and monitor the progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

In addition to its potential as a drug target and biomarker, KAP3 is also of interest to researchers because of its unique structure and function. The kappa-casein protein family is characterized by the presence of a variable region, which is responsible for the unique structure and function of the protein. This variable region is the source of KAP3's unique properties and allows it to interact with other proteins, such as TTR, and participate in a wide range of physiological processes.

Overall, KAP3 is a protein that has the potential to be a drug target and biomarker for a variety of diseases. Further research is needed to fully understand its unique properties and its potential as a drug.

Protein Name: Kinesin Associated Protein 3

Functions: Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Binds to the tail domain of the KIF3A/KIF3B heterodimer to form a heterotrimeric KIF3 complex and may regulate the membrane binding of this complex (By similarity)

The "KIFAP3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KIFAP3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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