KIR2DP1: A Potential Drug Target and Biomarker (G554300)

Target Name: KIR2DP1

NCBI ID: G554300

KIR2DP1

KIR2DP1: A Potential Drug Target and Biomarker

Killer Cell Immunoglobulin Like Receptor (KIR2DP1) is a protein that is expressed in various tissues of the body, including the spleen, thymus, spleen-lymph node complex, and Peyer's patches. It is a member of the immunoglobulinlike receptor (Iglike receptor) family 2 (ILR2) and has been identified as a potential drug target in the field of immunology.

KIR2DP1 is a 21-kDa protein that consists of two Ig domains, a constant region, and a variable region. The constant region of KIR2DP1 consists of 121 amino acids and includes a single constant region domain that is involved in the formation of the interface between the extracellular domain and the transmembrane domain. The variable region of KIR2DP1 consists of 81 amino acids and includes a single variable region domain that is involved in the formation of the interface between the transmembrane domain and the intracellular domain.

KIR2DP1 is involved in the immune response and has been shown to play a role in the regulation of inflammation and autoimmunity. KIR2DP1 has been shown to interact with various intracellular signaling pathways, including the T cell signaling pathway and the B cell signaling pathway.

One of the potential drug targets for KIR2DP1 is the inhibition of its activity. The development of inhibitors that can specifically target KIR2DP1 has the potential to be a valuable tool in the treatment of various autoimmune diseases, including rheumatoid arthritis, lupus, and multiple sclerosis.

Another potential drug target for KIR2DP1 is the stimulation of its activity. The activation of KIR2DP1 has been shown to have a positive impact on the production of immune cells, including T cells and B cells, which are important for the immune response. The stimulation of KIR2DP1 has also been shown to have a positive impact on the activity of immune cells, including the production of antibodies.

In addition to its potential as a drug target, KIR2DP1 is also a potential biomarker. The expression of KIR2DP1 has been shown to be elevated in various diseases, including autoimmune diseases, which suggests that KIR2DP1 may be a useful biomarker for the diagnosis and assessment of these diseases.

Overall, KIR2DP1 is a protein that has the potential to be a drug target and a biomarker. Further research is needed to fully understand its role in the immune response and to develop effective inhibitors or activators of its activity.

Protein Name: Killer Cell Immunoglobulin Like Receptor, Two Ig Domains Pseudogene 1

The "KIR2DP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KIR2DP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets