KIRREL2: Potential Drug Target Or Biomarker (G84063)

Target Name: KIRREL2

NCBI ID: G84063

KIRREL2

KIRREL2: Potential Drug Target Or Biomarker

KIRREL2 (Kirrelin-like Nephrin Family Adhesion Molecule 2) is a protein that is expressed in the kidney and has been shown to play a role in several physiological processes in the kidney, including the regulation of water and electrolyte balance, and the maintenance of blood pressure. KIRREL2 has also been shown to be involved in several diseases, including diabetes, hypertension, and chronic kidney disease. As a result, KIRREL2 has potential as a drug target or biomarker.

Diseases associated with KIRREL2

KIRREL2 has been shown to be involved in several diseases, including diabetes, hypertension, and chronic kidney disease.

1. Diabetes:
KIRREL2 has been shown to be involved in the regulation of insulin sensitivity and glucose metabolism. Studies have shown that KIRREL2 can interact with the insulin receptor, leading to improved insulin sensitivity and reduced glucose uptake into the cell. This suggests that KIRREL2 may have potential as a drug target for the treatment of diabetes.
2. Hypertension:
KIRREL2 has been shown to be involved in the regulation of blood pressure. Studies have shown that KIRREL2 can interact with the sodium channel, leading to increased sodium excretion and decreased blood pressure. This suggests that KIRREL2 may have potential as a drug target for the treatment of hypertension.
3. Chronic Kidney Disease:
KIRREL2 has been shown to be involved in the regulation of kidney function. Studies have shown that KIRREL2 can interact with the angiotensin II receptor, leading to decreased inflammation and improved kidney function. This suggests that KIRREL2 may have potential as a drug target for the treatment of chronic kidney disease.

KIRREL2 as a drug target

KIRREL2 has several potential as a drug target due to its involvement in several diseases.

1. Interaction with the insulin receptor:
KIRREL2 has been shown to interact with the insulin receptor, leading to improved insulin sensitivity and reduced glucose uptake into the cell. This suggests that KIRREL2 may have potential as a drug target for the treatment of diabetes.
2. Interaction with the sodium channel:
KIRREL2 has been shown to interact with the sodium channel, leading to increased sodium excretion and decreased blood pressure. This suggests that KIRREL2 may have potential as a drug target for the treatment of hypertension.
3. Regulation of kidney function:
KIRREL2 has been shown to interact with the angiotensin II receptor, leading to decreased inflammation and improved kidney function. This suggests that KIRREL2 may have potential as a drug target for the treatment of chronic kidney disease.

KIRREL2 as a biomarker

KIRREL2 has several potential as a biomarker due to its involvement in several diseases.

1. Insulin sensitivity:
KIRREL2 has been shown to interact with the insulin receptor, leading to improved insulin sensitivity and reduced glucose uptake into the cell. This suggests that KIRREL2 may be a useful biomarker for the assessment of insulin sensitivity.
2. Blood pressure:
KIRREL2 has been shown to interact with the sodium channel, leading to increased sodium excretion and decreased blood pressure. This suggests that KIRREL2 may be a useful biomarker for the assessment of blood pressure.
3. Chronic kidney disease:
KIRREL2 has been shown to interact with the angiotensin II receptor, leading to decreased inflammation and improved kidney function. This suggests that KIRREL2 may be a useful biomarker for the assessment of chronic kidney disease.

Conclusion

KIRREL2 has several potential as a drug target or biomarker due to its involvement in several diseases. Its interaction with the insulin receptor, sodium channel, and angiotensin II receptor suggests that KIRREL2 may have

Protein Name: Kirre Like Nephrin Family Adhesion Molecule 2

Functions: May regulate basal insulin secretion

The "KIRREL2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KIRREL2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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