Target Name: KLHL13
NCBI ID: G90293
Review Report on KLHL13 Target / Biomarker Content of Review Report on KLHL13 Target / Biomarker
KLHL13
Other Name(s): FLJ10262 | Kelch-like 13 | KLH13_HUMAN | Kelch-like protein 13 (isoform a) | Kelch like family member 13, transcript variant 1 | Kelch-like protein 13 (isoform d) | BTB and kelch domain-containing protein 2 | Kelch like family member 13, transcript variant 4 | KIAA1309 | MGC74791 | BTB and kelch domain containing 2 | BKLHD2 | Kelch-like protein 13 | kelch-like 13 | kelch like family member 13 | KLHL13 variant 4 | KLHL13 variant 1

KLHL13: A Protein Involved in Cellular Processes and Potential Drug & Biomarker Targets

KLHL13 (FLJ10262) is a protein that is expressed in various tissues of the body, including the brain, heart, and liver. It is a member of the heat shock protein (HSP) family, which are proteins that are expressed in response to increased levels of thermal stress in the cell.

One of the functions of KLHL13 is to regulate the expression of other genes. It has been shown to play a role in the regulation of cell proliferation, differentiation, and survival.

KLHL13 has also been shown to be involved in the regulation of inflammation. It has been shown to play a role in the recruitment of immune cells to sites of infection, and to contribute to the immune response.

In addition to its role in cell regulation and inflammation, KLHL13 has also been shown to be involved in the regulation of tissue repair and regeneration. It has been shown to play a role in the regulation of cell proliferation and survival in the repair of damaged tissue, and to contribute to the formation of new tissues during wound healing.

KLHL13 is also a potential drug target. Several studies have shown that KLHL13 is involved in a wide range of cellular processes that are important for human health, and that it is potential for use in a variety of therapeutic applications.

One potential mechanism by which KLHL13 could be used as a drug target is its role in the regulation of cell proliferation. KLHL13 has been shown to play a negative role in cell proliferation, and it has been shown to inhibit the growth of cancer cells. This could make it a useful target for therapies aimed at combating cancer.

Another potential mechanism by which KLHL13 could be used as a drug target is its role in the regulation of inflammation. KLHL13 has been shown to contribute to the recruitment of immune cells to sites of infection, and it has been shown to play a role in the regulation of the immune response. This could make it a useful target for therapies aimed at reducing inflammation and improving immune function.

In addition to its potential as a drug target, KLHL13 is also a potential biomarker. Several studies have shown that KLHL13 is expressed in a wide range of tissues and that it is involved in the regulation of a variety of cellular processes. This could make it a useful biomarker for a variety of diseases, including cancer, cardiovascular disease, and neurodegenerative diseases.

Overall, KLHL13 is a protein that is involved in a wide range of cellular processes that are important for human health. Its potential as a drug target and as a biomarker makes it a promising target for therapies aimed at improving human health. Further research is needed to fully understand the role of KLHL13 in cellular processes and to develop effective therapies.

Protein Name: Kelch Like Family Member 13

Functions: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis

The "KLHL13 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KLHL13 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

KLHL14 | KLHL15 | KLHL17 | KLHL18 | KLHL2 | KLHL20 | KLHL21 | KLHL22 | KLHL23 | KLHL24 | KLHL25 | KLHL26 | KLHL28 | KLHL29 | KLHL3 | KLHL30 | KLHL30-AS1 | KLHL31 | KLHL32 | KLHL33 | KLHL34 | KLHL35 | KLHL36 | KLHL38 | KLHL4 | KLHL40 | KLHL41 | KLHL42 | KLHL5 | KLHL6 | KLHL7 | KLHL7-DT | KLHL8 | KLHL9 | KLK1 | KLK10 | KLK11 | KLK12 | KLK13 | KLK14 | KLK15 | KLK2 | KLK3 | KLK4 | KLK5 | KLK6 | KLK7 | KLK8 | KLK9 | KLKB1 | KLKP1 | KLLN | KLRA1P | KLRB1 | KLRC1 | KLRC2 | KLRC3 | KLRC4 | KLRC4-KLRK1 | KLRD1 | KLRF1 | KLRF2 | KLRG1 | KLRG2 | KLRK1 | KLRK1-AS1 | KMO | KMT2A | KMT2B | KMT2C | KMT2CP4 | KMT2D | KMT2E | KMT2E-AS1 | KMT5A | KMT5B | KMT5C | KNCN | KNDC1 | KNG1 | KNL1 | KNOP1 | KNOP1P5 | KNSTRN | KNTC1 | KPNA1 | KPNA2 | KPNA3 | KPNA4 | KPNA5 | KPNA6 | KPNA7 | KPNB1 | KPNB1-DT | KPRP | KPTN | KRAS | KRASP1 | KRBA1 | KRBA2