Target Name: KIR3DS1
NCBI ID: G3813
Review Report on KIR3DS1 Target / Biomarker Content of Review Report on KIR3DS1 Target / Biomarker
KIR3DS1
Other Name(s): MHC class I NK cell receptor | killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 | KIR-123FM | NKAT10 | MGC119726 | CD158E2 | MGC125316 | Natural killer-associated transcript 10 | NKAT-10 | Killer cell immunoglobulin-like receptor 3DS1 (isoform 1) | KI3S1_HUMAN | killer cell immunoglobulin-like receptor KIR3DS1 | killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1 | Killer cell immunoglobulin-like receptor KIR3DS1 | Killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1, transcript variant 1 | KIR3DS1 variant 1 | natural killer-associated transcript 10 | MGC119728 | KIR-G1 | Killer cell immunoglobulin-like receptor 3DS1

KIR3DS1: The Potential Drug Target and Biomarker for NK Cell Receptor

Natural killers (NK cells) are a crucial part of the immune system, which are responsible for eliminating infected and mutated cells. NK cells, also known as cytotoxic T-cells, are a type of immune cell that can detect and destroy mutated or infected cells in the body. NK cells have the potential to be used as a drug target or biomarker due to their ability to targetedly destroy cancer cells. One of the potential drug targets for NK cells is the KIR3DS1 receptor, which is a type of NK cell receptor that is expressed in a variety of tissues throughout the body. In this article, we will discuss the potential drug target and biomarker for NK cell receptor KIR3DS1.

The KIR3DS1 Receptor

The KIR3DS1 receptor is a type of NK cell receptor that is expressed in various tissues throughout the body, including the brain, spleen, skin, and lymphoid organs. The KIR3DS1 receptor is involved in the process of cell-mediated immunity, which is the body's first line of defense against infection and disease.

The KIR3DS1 receptor is composed of a extracellular domain that is responsible for the formation of the receptor complex, a transmembrane domain that is responsible for transmitting signals between the receptor and intracellular signaling pathways, and an intracellular domain that is responsible for interacting with intracellular signaling pathways. The KIR3DS1 receptor has been shown to play a role in a variety of physiological processes, including immune surveillance, inflammation, and tissue repair.

Due to its involvement in cell-mediated immunity, the KIR3DS1 receptor has the potential to be used as a drug target for cancer. One of the potential mechanisms by which KIR3DS1 can be used as a drug target is through its role in the immune response. Cancer cells have the ability to evade the immune response by suppressing the activity of NK cells. By targeting the KIR3DS1 receptor, drugs can restore the activity of NK cells and enhance their ability to detect and destroy cancer cells.

In addition to its potential as a drug target, KIR3DS1 has also been shown to be a potential biomarker for cancer. The KIR3DS1 receptor is expressed in various tissues throughout the body, including the bloodstream, lymph nodes, and other organs. By detecting the expression of KIR3DS1 in cancer cells, researchers can monitor the effectiveness of different treatments and determine the potential for new treatments.

Targeting KIR3DS1

Despite the potential benefits of targeting the KIR3DS1 receptor, the development of drugs that can specifically inhibit the KIR3DS1 receptor is still a challenging task. Currently, there are few FDA-approved drugs that can specifically target the KIR3DS1 receptor. The most common classes of drugs that target the KIR3DS1 receptor are inhibitors of DNA-protein binding, such as inhibitors of the DNA-protein binding complex subunits that are involved in the formation of the KIR3DS1 receptor.

An inhibitor of the DNA-protein binding complex subunit that is involved in the formation of the KIR3DS1 receptor, such as valproic acid, has been shown to be effective in preclinical studies in treating various types of cancer. Valproic acid is an inhibitor of the DNA-protein binding complex subunit called DNA-protein binding protein (DABP), which is a key component of the KIR3DS1 receptor.

Another class of drugs that may target the KIR3DS1 receptor are small molecules that can specifically interact with the KIR3DS1 receptor. One of the most promising small molecules that can

Protein Name: Killer Cell Immunoglobulin Like Receptor, Three Ig Domains And Short Cytoplasmic Tail 1

Functions: Receptor on natural killer (NK) cells for MHC class I molecules. Upon interaction with peptide-free HLA-F open conformer, triggers NK cell degranulation and anti-viral cytokine production

The "KIR3DS1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KIR3DS1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

KIR3DX1 | KIRREL1 | KIRREL1-IT1 | KIRREL2 | KIRREL3 | KIRREL3-AS2 | KIRREL3-AS3 | KISS1 | KISS1R | KIT | KITLG | KIZ | KIZ-AS1 | KL | KLB | KLC1 | KLC2 | KLC3 | KLC4 | KLF1 | KLF10 | KLF11 | KLF12 | KLF13 | KLF14 | KLF15 | KLF16 | KLF17 | KLF17P1 | KLF2 | KLF3 | KLF3-AS1 | KLF4 | KLF5 | KLF6 | KLF7 | KLF8 | KLF9 | KLHDC1 | KLHDC10 | KLHDC2 | KLHDC3 | KLHDC4 | KLHDC7A | KLHDC7B | KLHDC7B-DT | KLHDC8A | KLHDC8B | KLHDC9 | KLHL1 | KLHL10 | KLHL11 | KLHL12 | KLHL13 | KLHL14 | KLHL15 | KLHL17 | KLHL18 | KLHL2 | KLHL20 | KLHL21 | KLHL22 | KLHL23 | KLHL24 | KLHL25 | KLHL26 | KLHL28 | KLHL29 | KLHL3 | KLHL30 | KLHL30-AS1 | KLHL31 | KLHL32 | KLHL33 | KLHL34 | KLHL35 | KLHL36 | KLHL38 | KLHL4 | KLHL40 | KLHL41 | KLHL42 | KLHL5 | KLHL6 | KLHL7 | KLHL7-DT | KLHL8 | KLHL9 | KLK1 | KLK10 | KLK11 | KLK12 | KLK13 | KLK14 | KLK15 | KLK2 | KLK3 | KLK4 | KLK5 | KLK6