Target Name: KIR2DS4
NCBI ID: G3809
Review Report on KIR2DS4 Target / Biomarker Content of Review Report on KIR2DS4 Target / Biomarker
KIR2DS4
Other Name(s): MHC class I NK cell receptor | Natural killer-associated transcript 8 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 | killer inhibitory receptor 4-1-2 | p50 killer cell activating receptor KAR-K1d | KKA3 | Natural killer cell inhibitory receptor | KIR1D | CL-17 | KIR2DS4 variant 1 | Killer cell immunoglobulin-like receptor 2DS4 (isoform 1) | CD158 antigen-like family member I | CD158i | killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4 | KIR412 | MGC125315 | NKAT-8 | Killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4, transcript variant 1 | P58 natural killer cell receptor clone CL-39 | KIR antigen 2DS4 | P58 NK receptor | KIR-2DS4 | Killer inhibitory receptor 4-1-2 | Killer cell immunoglobulin-like receptor 2DS4 | KI2S4_HUMAN | p58 NK receptor CL-39/CL-17 | NKAT8 | MGC125317 | MGC120019 | natural killer-associated transcript 8 | killer cell immunoglobulin-like receptor 2DS1-like | CD158I | P58 natural killer cell receptor clones CL-39/CL-17

KIR2DS4: A Non-Coding RNA Molecule Implicated in NK Cell Function and Cancer

The KIR2DS4 gene is a non-coding RNA molecule that is located on chromosome 6p21.2 and has been identified as a potential drug target or biomarker for several diseases, including cancer.

The immune system is a critical component of our bodies that helps to protect us from infection and disease. NK cells, also known as natural killer cells, are a type of immune cell that play a crucial role in detecting and eliminating infected or abnormal cells in the body.

KIR2DS4 is a non-coding RNA molecule that is expressed in many different tissues and cells in the body. It is located on chromosome 6p21.2 and has been shown to be involved in the development and function of NK cells.

Studies have shown that KIR2DS4 is involved in the regulation of NK cell proliferation, differentiation, and survival. It has been shown to play a role in the development of cancer, including melanoma, skin cancer, and leukemia.

In addition to its role in cancer, KIR2DS4 has also been shown to be involved in several other diseases, including autoimmune disorders, such as rheumatoid arthritis and psoriasis. It has also been shown to be involved in the regulation of inflammation and pain.

Given its involvement in so many different diseases and its potential as a drug target, KIR2DS4 is an attractive target for researchers to study and potentially develop into a new drug or therapy.

Research into KIR2DS4 has been ongoing for several years, and there is a growing body of research that is focused on its potential as a drug target. Several studies have shown that KIR2DS4 can be effectively targeted with small molecules, antibodies, and other therapeutic agents.

One of the most promising strategies for studying KIR2DS4 is the use of small molecules that can interact with the RNA molecule. These small molecules can be used to inhibit the activity of KIR2DS4 and prevent it from regulating the activity of NK cells.

Another approach to studying KIR2DS4 is the use of antibodies that are designed to recognize and bind to the RNA molecule. These antibodies can be used to study the structure and function of KIR2DS4, and to determine the ways in which it interacts with NK cells.

In addition to these studies, researchers have also used other techniques to study the role of KIR2DS4 in cancer and other diseases. For example, they have used RNA interference techniques to knock down the expression of KIR2DS4 in cancer cells and to study its effects on cell growth and survival.

Overall, the KIR2DS4 gene is a promising target for research into the role of NK cells and their role in cancer and other diseases. Further studies are needed to fully understand the ways in which KIR2DS4 interacts with NK cells and to determine its potential as a drug target.

Protein Name: Killer Cell Immunoglobulin Like Receptor, Two Ig Domains And Short Cytoplasmic Tail 4

Functions: Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells

The "KIR2DS4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KIR2DS4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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KIR2DS5 | KIR3DL1 | KIR3DL2 | KIR3DL3 | KIR3DP1 | KIR3DS1 | KIR3DX1 | KIRREL1 | KIRREL1-IT1 | KIRREL2 | KIRREL3 | KIRREL3-AS2 | KIRREL3-AS3 | KISS1 | KISS1R | KIT | KITLG | KIZ | KIZ-AS1 | KL | KLB | KLC1 | KLC2 | KLC3 | KLC4 | KLF1 | KLF10 | KLF11 | KLF12 | KLF13 | KLF14 | KLF15 | KLF16 | KLF17 | KLF17P1 | KLF2 | KLF3 | KLF3-AS1 | KLF4 | KLF5 | KLF6 | KLF7 | KLF8 | KLF9 | KLHDC1 | KLHDC10 | KLHDC2 | KLHDC3 | KLHDC4 | KLHDC7A | KLHDC7B | KLHDC7B-DT | KLHDC8A | KLHDC8B | KLHDC9 | KLHL1 | KLHL10 | KLHL11 | KLHL12 | KLHL13 | KLHL14 | KLHL15 | KLHL17 | KLHL18 | KLHL2 | KLHL20 | KLHL21 | KLHL22 | KLHL23 | KLHL24 | KLHL25 | KLHL26 | KLHL28 | KLHL29 | KLHL3 | KLHL30 | KLHL30-AS1 | KLHL31 | KLHL32 | KLHL33 | KLHL34 | KLHL35 | KLHL36 | KLHL38 | KLHL4 | KLHL40 | KLHL41 | KLHL42 | KLHL5 | KLHL6 | KLHL7 | KLHL7-DT | KLHL8 | KLHL9 | KLK1 | KLK10 | KLK11 | KLK12 | KLK13 | KLK14