Target Name: KIR3DL1
NCBI ID: G3811
Review Report on KIR3DL1 Target / Biomarker Content of Review Report on KIR3DL1 Target / Biomarker
KIR3DL1
Other Name(s): MHC class I NK cell receptor | KIR3DL1*063 | KIR2DL5B*00805 | NKB1B | KIR3DL2*00103 | KIR3DL1 variant 1 (reference allele) | KIR2DL5B*00601 | Natural killer-associated transcript 3 | KIR2DL5B*011 | MGC126589 | CD158 antigen-like family member E | KIR3DL1/S1 | KIR3DL2*00202 | killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 | KIR antigen 3DL1 | MGC119726 | KIR3DL2*00101 | NK-receptor | KIR3DL1*00501 | KIR3DL1*00701 | KIR3DL1*00101 | NKAT-3 | killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 | MGC126591 | CD158E1 | KI3L1_HUMAN | Killer cell immunoglobulin-like receptor 3DL1 | KIR3DL1*00401 | NKB1 | Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1, transcript variant 1 (reference allele) | Killer cell immunoglobulin-like receptor 3DL1 (isoform 1) | p70 natural killer cell receptor clones CL-2/CL-11 | p70 killer cell inhibitory receptor | KIR | natural killer-associated transcript 3 | p70 NK receptor CL-2/CL-11 | NKAT3 | CD158e | HLA-BW4-specific inhibitory NK cell receptor | KIR2DL5B | MGC119728

KIR3DL1: Member of The MHC Class I Molecules and Regulator of T Cell Activity

The KIR3DL1 gene is a member of the immune checkpoint receptor family, which includes four isoforms: KIR3DL1, KIR3DL2, KIR3DL3, and KIR3DL4. These proteins are involved in the immune response and play a crucial role in regulating the regulation of T cells. KIR3DL1 is a protein that is expressed in most tissues of the body and is known to be involved in the immune response.

KIR3DL1 is a member of the MHC class I molecules, which are a type of antigen presenting cell that is responsible for presenting foreign antigens to T cells. MHC class I molecules are composed of a constant region and two variable regions. The constant region is the region of the protein that is constant between different isoforms, while the variable regions are the regions of the protein that are different between the isoforms.

KIR3DL1 is a 14-kDa protein that is expressed in most tissues of the body. It is primarily expressed in the spleen, lymph nodes, and thymus, but is also found in the skin, hair, and eyes. KIR3DL1 is also expressed in the bone marrow and in the placenta, and is thought to play a role in immune surveillance of the bone marrow.

KIR3DL1 is involved in the immune response by regulating the activity of T cells. T cells are a type of immune cell that play a crucial role in protecting the body against infection and disease. T cells are divided into two different types: helper T cells and memory T cells. Helper T cells, also known as T cell alpha delta, are a type of T cell that are responsible for producing antibodies. Memory T cells, also known as T cell memory, are a type of T cell that have been exposed to a pathogen in the past and are responsible for remembering the pathogen and responding to it in the future.

KIR3DL1 is involved in the regulation of the activity of T cells by interacting with the PD-1 receptor, which is a protein that is expressed in most tissues of the body. PD-1 is a transmembrane protein that is involved in cell signaling. It is expressed in most tissues of the body and is involved in the regulation of many different processes in the body, including immune surveillance.

KIR3DL1 is also involved in the regulation of the activity of T cells by interacting with the CTLA-4 receptor, which is a protein that is expressed in most tissues of the body. CTLA-4 is a transmembrane protein that is involved in cell signaling. It is expressed in most tissues of the body and is involved in the regulation of many different processes in the body, including immune surveillance.

KIR3DL1 is also involved in the regulation of the activity of T cells by interacting with the PD-L1 receptor, which is a protein that is expressed in most tissues of the body. PD-L1 is a transmembrane protein that is involved in cell signaling. It is expressed in most tissues of the body and is involved in the regulation of many different processes in the body, including immune surveillance.

In conclusion, KIR3DL1 is a protein that is involved in the immune response. It is expressed in most tissues of the body and is thought to play a role in regulating the activity of T cells. KIR3DL1 is involved in the immune response by interacting with the PD-1, CTLA-4, and PD-L1 receptors. These interactions may provide a target for the development of new drugs or biomarkers for the treatment of immune-related disorders. Further research is needed to fully understand the role of KIR3DL1 in the immune response and to develop new treatments based on this protein.

Protein Name: Killer Cell Immunoglobulin Like Receptor, Three Ig Domains And Long Cytoplasmic Tail 1

Functions: Receptor on natural killer (NK) cells for HLA Bw4 allele. Inhibits the activity of NK cells thus preventing cell lysis

The "KIR3DL1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KIR3DL1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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KIR3DL2 | KIR3DL3 | KIR3DP1 | KIR3DS1 | KIR3DX1 | KIRREL1 | KIRREL1-IT1 | KIRREL2 | KIRREL3 | KIRREL3-AS2 | KIRREL3-AS3 | KISS1 | KISS1R | KIT | KITLG | KIZ | KIZ-AS1 | KL | KLB | KLC1 | KLC2 | KLC3 | KLC4 | KLF1 | KLF10 | KLF11 | KLF12 | KLF13 | KLF14 | KLF15 | KLF16 | KLF17 | KLF17P1 | KLF2 | KLF3 | KLF3-AS1 | KLF4 | KLF5 | KLF6 | KLF7 | KLF8 | KLF9 | KLHDC1 | KLHDC10 | KLHDC2 | KLHDC3 | KLHDC4 | KLHDC7A | KLHDC7B | KLHDC7B-DT | KLHDC8A | KLHDC8B | KLHDC9 | KLHL1 | KLHL10 | KLHL11 | KLHL12 | KLHL13 | KLHL14 | KLHL15 | KLHL17 | KLHL18 | KLHL2 | KLHL20 | KLHL21 | KLHL22 | KLHL23 | KLHL24 | KLHL25 | KLHL26 | KLHL28 | KLHL29 | KLHL3 | KLHL30 | KLHL30-AS1 | KLHL31 | KLHL32 | KLHL33 | KLHL34 | KLHL35 | KLHL36 | KLHL38 | KLHL4 | KLHL40 | KLHL41 | KLHL42 | KLHL5 | KLHL6 | KLHL7 | KLHL7-DT | KLHL8 | KLHL9 | KLK1 | KLK10 | KLK11 | KLK12 | KLK13 | KLK14 | KLK15 | KLK2