KLHL21: A Potential Drug Target and Biomarker (G9903)

Target Name: KLHL21

NCBI ID: G9903

KLHL21

KLHL21: A Potential Drug Target and Biomarker

Kelch-like family member 21 (KLHL21) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker. KLHL21 is a key regulator of the T-cell receptor (TCR), which is a critical molecule that plays a crucial role in the immune system. TCR is composed of a variable region and a constant region, and it is expressed in a variety of tissues, including the brain, spinal cord, and thymus. KLHL21 is a key regulator of TCR development and function, and it has been shown to play a role in the regulation of immune cell proliferation and differentiation.

KLHL21 is a small molecule that can interact with the TCR. It is expressed in high levels in the brain and spinal cord, and it has been shown to play a role in the regulation of neural cell proliferation and differentiation. KLHL21 has also been shown to interact with the protein PDGF-BB, which is a key regulator of TCR development and function.

One of the most promising aspects of KLHL21 is its potential as a drug target. KLHL21 has been shown to play a role in the regulation of TCR function, and it is possible that it may be a useful target for the development of new immunotherapeutic drugs. For example, KLHL21 has been shown to interact with the TCR and to regulate the expression of genes involved in TCR development and function. This suggests that KLHL21 may be a useful target for the development of new immunotherapeutic drugs that target the TCR.

In addition to its potential as a drug target, KLHL21 has also been shown to be a potential biomarker. KLHL21 is a highly conserved gene that is expressed in a variety of tissues, including the brain, spinal cord, and thymus. This suggests that KLHL21 may be a useful biomarker for the diagnosis and prognosis of a variety of diseases. For example, KLHL21 has been shown to be expressed in the brains of individuals with Alzheimer's disease, and it has been suggested that it may be a potential target for the development of new therapies for this disease.

KLHL21 is a small molecule that has been shown to play a critical role in the regulation of TCR function and development. It is a potential drug target and biomarker, and it has the potential to be used in the development of new immunotherapeutic drugs and therapies for a variety of diseases. Further research is needed to fully understand the role of KLHL21 in the immune system and its potential as a drug target and biomarker.

Protein Name: Kelch Like Family Member 21

Functions: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome

The "KLHL21 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KLHL21 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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