Target Name: UBR4
NCBI ID: G23352
Review Report on UBR4 Target / Biomarker Content of Review Report on UBR4 Target / Biomarker
UBR4
Other Name(s): UBR4_HUMAN | Retinoblastoma-associated factor of 600 kDa | p600 | retinoblastoma-associated factor of 600 kDa | FLJ41863 | RING-type E3 ubiquitin transferase UBR4 | zinc finger UBR1-type protein 1 | RP5-1126H10.1 | RBAF600 | N-recognin-4 | Retinoblastoma-associated factor 600-like protein | OTTHUMP00000002585 | ubiquitin protein ligase E3 component n-recognin 4 | MTAF600 | KIAA0462 | ZUBR1 | retinoblastoma-associated factor 600-like protein | E3 ubiquitin-protein ligase UBR4 | KIAA1307 | Zinc finger UBR1-type protein 1 | 600 kDa retinoblastoma protein-associated factor | Ubiquitin protein ligase E3 component n-recognin 4

Understanding The Potential Applications of UBR4

UBR4 (UBR4_HUMAN) is a protein that is expressed in human tissues and has been identified as a potential drug target or biomarker. UBR4 is a member of the UBR4 gene family, which is known for its role in the regulation of cell growth and differentiation.

UBR4 has been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its role in these processes is not well understood, but it is known to be involved in the regulation of cell-cell adhesion, a process that is critical for the development and maintenance of tissues and organs.

One of the most promising aspects of UBR4 is its potential as a drug target. Researchers have identified several potential drug candidates that target UBR4, and these compounds have been shown to have a variety of biological effects, including inhibition of cell growth, cell division, and migration. In addition, UBR4 has been shown to play a role in the regulation of angiogenesis, the process by which new blood vessels are formed, which can be a potential target for diseases that are characterized by the buildup of blood vessels or the failure of blood vessels to properly function.

Another potential application of UBR4 is as a biomarker for certain diseases. The regulation of cell-cell adhesion is a critical process that is involved in the development and maintenance of tissues and organs, and disruptions in this process have been implicated in the development of many diseases. For example, UBR4 has been shown to be involved in the regulation of tissue engineering and regeneration, and disruptions in this process have been linked to the development of tissue engineering and regeneration disorders. In addition, UBR4 has been shown to play a role in the regulation of stem cell maintenance and proliferation, which is critical for the development and maintenance of tissues and organs.

Overall, UBR4 is a protein that has the potential to be a drug target or biomarker for a variety of diseases. Further research is needed to fully understand its role in these processes and to develop effective treatments for diseases that are characterized by disruptions in cell-cell adhesion.

Protein Name: Ubiquitin Protein Ligase E3 Component N-recognin 4

Functions: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Regulates integrin-mediated signaling. May play a role in activation of FAK in response to cell-matrix interactions. Mediates ubiquitination of ACLY, leading to its subsequent degradation

The "UBR4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about UBR4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

UBR5 | UBR5-DT | UBR7 | UBTD1 | UBTD2 | UBTF | UBTFL1 | UBTFL2 | UBTFL6 | UBXN1 | UBXN10 | UBXN11 | UBXN2A | UBXN2B | UBXN4 | UBXN6 | UBXN7 | UBXN8 | UCA1 | UCHL1 | UCHL1-DT | UCHL3 | UCHL5 | UCK1 | UCK2 | UCKL1 | UCKL1-AS1 | UCMA | UCN | UCN2 | UCN3 | UCP1 | UCP2 | UCP3 | UDP-Glycosyltransferase | UDP-N-Acetylglucosamine--Peptide N-Acetylglucosaminyltransferase (O-GlcNAc Transferase) | UEVLD | UFC1 | UFD1 | UFD1-AS1 | UFL1 | UFM1 | UFSP1 | UFSP2 | UGCG | UGDH | UGDH-AS1 | UGGT1 | UGGT2 | UGP2 | UGT1A1 | UGT1A10 | UGT1A3 | UGT1A4 | UGT1A5 | UGT1A6 | UGT1A7 | UGT1A8 | UGT1A9 | UGT2A1 | UGT2A2 | UGT2A3 | UGT2B10 | UGT2B11 | UGT2B15 | UGT2B17 | UGT2B27P | UGT2B28 | UGT2B29P | UGT2B4 | UGT2B7 | UGT3A1 | UGT3A2 | UGT8 | UHMK1 | UHRF1 | UHRF2 | UICLM | UIMC1 | ULBP1 | ULBP2 | ULBP3 | ULK1 | ULK2 | ULK3 | ULK4 | ULK4P1 | ULK4P2 | ULK4P3 | UMAD1 | UMLILO | UMOD | UMODL1 | UMODL1-AS1 | UMPS | UNC119 | UNC119-myristate complex | UNC119B | UNC13A | UNC13B