Discovering New Insights Into UCK1: A Research Hotspot (G83549)

Target Name: UCK1

NCBI ID: G83549

UCK1

Discovering New Insights Into UCK1: A Research Hotspot

UCK1 (Uridine-cytidine kinase 1) is an enzyme that plays a critical role in the DNA replication process in eukaryotic cells. It is a protein that is expressed in various cell types, including muscle, liver, and brain cells. UCK1 is involved in the repair of DNA damage caused by various mechanisms, including exposure to radiation, UV radiation, and certain drugs.

In addition to its role in DNA replication, UCK1 is also involved in the regulation of cell growth and differentiation. It has been shown to play a role in the regulation of cell cycle progression, and has been shown to be involved in the regulation of cell survival.

Given its involvement in so many cellular processes, UCK1 has naturally become a research hotspot among scientists. In recent years, researchers have discovered many drug targets and biomarkers related to UCK1.

This article will introduce the latest research progress of UCK1 as a drug target or biomarker.

First, UCK1's potential in treating cancer. Many cancers cause DNA damage, and UCK1 plays an important role in DNA repair and regeneration. Therefore, UCK1 has become an important cancer therapeutic target.

Currently, UCK1 has become the target of many cancer treatment drugs, including chemotherapy drugs, radiotherapy drugs and targeted drugs. For example, UCK1 inhibitors have become first-line drugs for the treatment of various cancers, including lung cancer, colorectal cancer, and kidney cancer.

In addition to being a drug target, UCK1 is also used as a biomarker. Researchers have discovered that UCK1 activity can serve as a biomarker in patients with certain cancers. For example, UCK1 activity can be detected as a tumor marker in lung and colorectal cancer patients.

In addition, UCK1 is also used to monitor the side effects of some drugs. Since UCK1 is expressed in many drugs, it is used as an indicator of side effects of many drugs. This helps doctors better evaluate a drug's efficacy and safety.

Overall, UCK1, as a drug target or biomarker, is of great significance in cancer treatment and drug research. As research deepens, UCK1 will continue to become

Protein Name: Uridine-cytidine Kinase 1

Functions: Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate (PubMed:11306702). Does not phosphorylate deoxyribonucleosides or purine ribonucleosides (PubMed:11306702). Can use ATP or GTP as a phosphate donor (PubMed:11306702). Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N(4)-anisoylcytidine (PubMed:11306702)

The "UCK1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about UCK1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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