UNC13B: A Protein Implicated in Cell Signaling, Ion Regulation, and Inflammation

Target Name: UNC13B

NCBI ID: G10497

UNC13B

UNC13B: A Protein Implicated in Cell Signaling, Ion Regulation, and Inflammation

UNC13B (munc13-2) is a protein that is expressed in various tissues throughout the body. It is a member of the uncan group of transmembrane proteins, which means that it spans the cell membrane and extends into the cytoplasm. UNC13B is involved in several cellular processes that are important for normal cell function, including cell signaling, inflammation, and the regulation of ion channels.

One of the key functions of UNC13B is its role in cell signaling. It is a signaling protein that is involved in the regulation of various signaling pathways, including the NF-kappa pathway. This pathway is involved in the regulation of cell growth, differentiation, and inflammation, and UNC13B is involved in the regulation of the activities of several transcription factors that are involved in these processes.

UNC13B is also involved in the regulation of ion channels. It is a protein that is involved in the regulation of the channels that allows calcium ions to enter the cells. This regulation is important for many cellular processes, including muscle contractions, nerve signaling, and blood pressure.

In addition to its role in cell signaling and ion regulation, UNC13B is also involved in the regulation of inflammation. It is a protein that is involved in the regulation of the production of pro-inflammatory cytokines, which are important for the response of the immune system to infection.

Despite its involvement in several important cellular processes, UNC13B is not well understood. There are currently no known drugs that are specifically targeted to UNC13B. However, this protein is an attractive candidate for drug development due to its involvement in several important cellular processes and its potential role as a drug target.

In conclusion, UNC13B is a protein that is involved in several important cellular processes, including cell signaling, ion regulation, and inflammation. While there are currently no known drugs that are specifically targeted to UNC13B, this protein is an attractive candidate for drug development due to its involvement in several important cellular processes and its potential role as a drug target. Further research is needed to fully understand the functions of UNC13B and its potential as a drug target.

Protein Name: Unc-13 Homolog B

Functions: Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP) (By similarity). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity). In collaboration with UNC13A, facilitates neuronal dense core vesicles fusion as well as controls the location and efficiency of their synaptic release (By similarity)

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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