Target Name: UBXN8
NCBI ID: G7993
Review Report on UBXN8 Target / Biomarker Content of Review Report on UBXN8 Target / Biomarker
UBXN8
Other Name(s): Reproduction 8 protein | UBX domain containing 6 | UBX domain-containing protein 6 | UBX domain protein 8 | UBX domain-containing protein 8 | UBXD6 | REP8 | D8S2298E | Reproduction/chromosome 8 | rep-8 protein | UBXN8_HUMAN | Rep-8 protein | reproduction 8 protein

UBXN8 Protein: Potential Drug Target for Neurological Disorders

The UBXN8 protein is a protein that is found in the nervous system that is known to play a role in the development and progression of various neurological disorders, including Alzheimer's disease. The protein is also known as Reproduction 8 protein and has been identified as a potential drug target for the treatment of these disorders.

The UBXN8 protein is a member of the superfamily of RNA-protein hybrids, which are also known as ribosome-binding proteins. It is a protein that is composed of a cytoplasmic alpha helix and ribosomal A protein domain. It is approximately 120 amino acids in length and its function plays a vital role in cells.

The UBXN8 protein plays a crucial role in the normal function of the nervous system. It is involved in many neuronal physiological processes, including signal transmission between neurons and between neurons and muscle cells. The UBXN8 protein is also closely associated with neuronal death and synaptic plasticity.

Abnormal expression of UBXN8 protein has been shown to be associated with many neurological diseases, including Alzheimer's disease. The disease is a neurodegenerative disorder that causes cognitive decline and ultimately death.

Several research groups have explored the potential role of the UBXN8 protein in treating neurological diseases. They found that the UBXN8 protein plays an important role in neuronal damage and neurodegenerative diseases, and that abnormal expression of the UBXN8 protein may be an important factor in these diseases.

In addition, the UBXN8 protein has also been considered as a potential drug target. Some researchers are exploring the use of small molecules to modulate the function of the UBXN8 protein to treat neurological diseases. They believe that these compounds can inhibit the abnormal expression of UBXN8 protein and thereby improve the function of the nervous system.

Normal function of UBXN8 protein in the nervous system

Protein Name: UBX Domain Protein 8

Functions: Involved in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins, possibly by tethering VCP to the endoplasmic reticulum membrane. May play a role in reproduction

The "UBXN8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about UBXN8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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