UBXN11: A Potential Drug Target for Neurological Disorders (G91544)

Target Name: UBXN11

NCBI ID: G91544

UBXN11

UBXN11: A Potential Drug Target for Neurological Disorders

UBXN11 (UBXN11 variant 2) is a protein that is expressed in the nervous system and has been identified as a potential drug target in the treatment of various neurological disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease.

The UBXN11 protein is a member of the superfamily of RNA-protein hybrids, which are composed of a protein core and a RNA molecule that is held in place by ionic bonds. UBXN11 is characterized by a unique arrangement of its amino acid residues, with several conserved structural features that are unique among RNA-protein hybrids.

One of the unique features of UBXN11 is its ability to interact with various types of RNA molecules, including microRNA (miRNA) and small interfering RNA (siRNA). This interaction between UBXN11 and RNA molecules is important for its function in the nervous system, as it allows the protein to regulate the expression of other genes and to play a role in the development and progression of various neurological disorders.

UBXN11 has been shown to play a role in the development and progression of Alzheimer's disease, one of the most common forms of dementia. Studies have shown that UBXN11 is overexpressed in the brains of individuals with Alzheimer's disease and that inhibiting its function may be a potential therapeutic approach for this disease.

In addition to its role in the development of Alzheimer's disease, UBXN11 has also been shown to be involved in the treatment of other neurological disorders. For example, studies have shown that UBXN11 may be a potential drug target for Parkinson's disease, a disorder that is characterized by the loss of motor neurons in the brain.

In addition to its potential therapeutic applications, UBXN11 is also of interest from a fundamental scientific standpoint. The unique arrangement of its amino acid residues and its ability to interact with various types of RNA molecules provide insights into the structure and function of RNA-protein hybrids and the mechanisms that regulate their interactions.

In conclusion, UBXN11 is a protein that has the potential to be a drug target for the treatment of various neurological disorders, including Alzheimer's disease and Parkinson's disease. Its unique structure and ability to interact with various types of RNA molecules make it an attractive target for manipulation with small molecules or other therapeutic approaches. Further research is needed to fully understand the role of UBXN11 in the development and treatment of neurological disorders and to develop safe and effective therapies based on this protein.

Protein Name: UBX Domain Protein 11

Functions: May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 and RND3. Promotes RHOA activation mediated by GNA12 and GNA13 (By similarity)

The "UBXN11 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about UBXN11 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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