Target Name: IFIT5
NCBI ID: G24138
Review Report on IFIT5 Target / Biomarker Content of Review Report on IFIT5 Target / Biomarker
IFIT5
Other Name(s): IFIT-5 | retinoic acid- and interferon-inducible 58 kDa protein | IFIT5_HUMAN | ISG58 | interferon-induced 58 kDa protein | OTTHUMP00000020063 | P58 | Retinoic acid- and interferon-inducible 58 kDa protein | Interferon induced protein with tetratricopeptide repeats 5 | Interferon-induced 58 kDa protein | FLJ92678 | retinoic acid- and interferon-inducible protein (58kD) | Interferon-induced protein with tetratricopeptide repeats 5 | RI58 | FLJ53857 | interferon induced protein with tetratricopeptide repeats 5

IFIT5: Protein Involved in Cell Signaling and Metabolism

IFIT5, also known as IFIT5A or ITF5, is a protein that is expressed in most tissues of the body. It is a member of the intercellular signaling molecule family 5 (IFITM), which includes proteins that play a critical role in cell signaling and metabolism. IFIT5 is a 21-kDa protein that is expressed in most tissues of the body, including muscle, heart, liver, and brain.

IFIT5 is involved in a wide range of cellular processes that are important for maintaining cellular homeostasis and regulating cellular signaling pathways. One of its most well-known functions is its role in the regulation of cellular metabolism, particularly the metabolism of lipids. IFIT5 is involved in the production and degradation of various lipids, including triacylglycerols (triglycerides) and fatty acids.

IFIT5 is also involved in the regulation of cellular signaling pathways that are important for cellular growth, differentiation, and inflammation. One of its most well-known functions is its role in the regulation of the TGF-β pathway, which is a critical pathway for cell signaling and growth. TGF-β is a cytokine that is involved in the regulation of cellular growth, differentiation, and inflammation. IFIT5 is involved in the regulation of TGF-β activity by interacting with its downstream receptor, SMAD4.

IFIT5 is also involved in the regulation of cellular signaling pathways that are important for cell survival and resistance to stress. One of its most well-known functions is its role in the regulation of apoptosis, which is the process by which cells undergo programmed cell death. IFIT5 is involved in the regulation of apoptosis by interacting with its downstream target, BCL2.

IFIT5 is also involved in the regulation of cellular signaling pathways that are important for cell signaling and inflammation. One of its most well-known functions is its role in the regulation of the NF-kappa-B pathway, which is a critical pathway for cell signaling and inflammation. NF-kappa-B is a transcription factor that is involved in the regulation of cellular signaling pathways that are important for cell growth, differentiation, and inflammation. IFIT5 is involved in the regulation of NF-kappa-B activity by interacting with its downstream receptor, IKK尾.

IFIT5 is also involved in the regulation of cellular signaling pathways that are important for cell signaling and metabolism. One of its most well-known functions is its role in the regulation of the PI3K/AKT signaling pathway, which is a critical pathway for cell signaling and metabolism. PI3K is a protein that is involved in the production of phosphatidylinositol (PI), which is a crucial component of cell signaling pathways. AKT is a protein that is involved in the regulation of cellular signaling pathways that are important for cell growth, differentiation, and metabolism. IFIT5 is involved in the regulation of PI3K/AKT activity by interacting with its downstream receptor, PDGFR-尾.

IFIT5 is also involved in the regulation of cellular signaling pathways that are important for cell signaling and metabolism. One of its most well-known functions is its role in the regulation of the TG-CSF signaling pathway, which is a critical pathway for cell signaling and metabolism. TG-CSF is a protein that is involved in the production of triacylglycerols (triglycerides), which are crucial sources of energy for cells. IFIT5 is involved in the regulation of TG-CSF activity by interacting with its downstream receptor, CSF2.

IFIT5 is also involved in the regulation of cellular signaling pathways that are important for

Protein Name: Interferon Induced Protein With Tetratricopeptide Repeats 5

Functions: Interferon-induced RNA-binding protein involved in the human innate immune response. Has a broad and adaptable RNA structure recognition important for RNA recognition specificity in antiviral defense. Binds precursor and processed tRNAs as well as poly-U-tailed tRNA fragments (PubMed:25092312, PubMed:23317505, PubMed:23774268). Specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner (PubMed:23334420). Also recognizes and selectively binds AT-rich dsDNA (PubMed:23774268). Additionally, as a mediator in innate immunity, regulates positively IKK-NFKB signaling by sinergizing the recruitment of IKK to MAP3K7 (PubMed:26334375)

The "IFIT5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about IFIT5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

IFITM1 | IFITM10 | IFITM2 | IFITM3 | IFITM3P2 | IFITM3P7 | IFITM4P | IFITM5 | IFITM8P | IFITM9P | IFNA1 | IFNA10 | IFNA12P | IFNA13 | IFNA14 | IFNA16 | IFNA17 | IFNA2 | IFNA21 | IFNA22P | IFNA4 | IFNA5 | IFNA6 | IFNA7 | IFNA8 | IFNAR1 | IFNAR2 | IFNB1 | IFNE | IFNG | IFNG-AS1 | IFNGR1 | IFNGR2 | IFNK | IFNL1 | IFNL2 | IFNL3 | IFNL4 | IFNLR1 | IFNW1 | IFNWP15 | IFNWP19 | IFRD1 | IFRD2 | IFT122 | IFT122P3 | IFT140 | IFT172 | IFT20 | IFT22 | IFT27 | IFT43 | IFT46 | IFT52 | IFT57 | IFT74 | IFT80 | IFT81 | IFT88 | IFTAP | IGBP1 | IGBP1P1 | IGDCC3 | IGDCC4 | IgE Receptors | IGF1 | IGF1R | IGF2 | IGF2-AS | IGF2BP1 | IGF2BP2 | IGF2BP2-AS1 | IGF2BP3 | IGF2R | IGFALS | IGFBP-AS1 | IGFBP1 | IGFBP2 | IGFBP3 | IGFBP4 | IGFBP5 | IGFBP6 | IGFBP7 | IGFBP7-AS1 | IGFBPL1 | IGFL1 | IGFL1P2 | IGFL2 | IGFL2-AS1 | IGFL3 | IGFL4 | IGFLR1 | IGFN1 | IGH@ | IGHA1 | IGHA2 | IGHD | IGHD1-1 | IGHD1-14 | IGHD1-20