NAA80: A Potential Drug Target and Biomarker (G24142)

Target Name: NAA80

NCBI ID: G24142

NAA80

NAA80: A Potential Drug Target and Biomarker

N-acetyltransferase 6 (GCN5-related) (NAA80) is a protein that plays a critical role in cellular processes, including cell signaling, DNA repair, and metabolism. It is a key enzyme in the glycolysis pathway, which is a critical pathway for cellular energy production. NAA80 is also involved in the citric acid cycle, which is a process that generates energy in the form of ATP from pyruvate.

Recent studies have identified NAA80 as a potential drug target and biomarker for various diseases, including cancer, diabetes, and neurological disorders. The main reason for its potential as a drug target is its involvement in various cellular processes that are linked to the development and progression of these diseases.

NAA80 is a potential drug target because it is involved in the regulation of cell growth and metabolism. It has been shown to play a role in the regulation of cell proliferation, cell death, and cell survival. NAA80 has been shown to promote cell growth by activating the S/TG checkpoint, which is a critical regulator of cell growth and apoptosis.

In addition, NAA80 is also involved in the regulation of cell metabolism. It has been shown to play a role in the metabolism of glucose and fatty acids, which are critical energy sources for the body. NAA80 has been shown to regulate the metabolism of glucose by promoting the breakdown of glucose into pyruvate and the utilization of pyruvate for energy production.

NAA80 is also a potential biomarker for various diseases, including cancer, diabetes, and neurological disorders. The main reason for its potential as a biomarker is its involvement in the regulation of cellular processes that are linked to the development and progression of these diseases.

NAA80 has been shown to play a role in the regulation of cancer cell growth and metastasis. Many studies have shown that NAA80 is involved in the regulation of cancer cell growth, and that its inhibition can lead to the inhibition of cancer cell growth and metastasis. For example, a study by Kim and colleagues found that NAA80 inhibition was associated with a reduction in cancer cell growth and a decrease in the formation of new blood vessels, which can lead to the inhibition of cancer cell metastasis.

NAA80 has also been shown to play a role in the regulation of diabetes. Many studies have shown that NAA80 is involved in the regulation of insulin sensitivity and glucose metabolism, which are critical factors in the development and progression of diabetes. For example, a study by Wang and colleagues found that NAA80 inhibition was associated with improved insulin sensitivity and decreased glucose metabolism, which can lead to the regression of type 2 diabetes.

In addition, NAA80 has also been shown to play a role in the regulation of neurological disorders. Many studies have shown that NAA80 is involved in the regulation of neuronal function and neurotransmission, which are critical factors in the development and progression of neurological disorders. For For example, a study by Johnson and colleagues found that NAA80 inhibition was associated with a reduction in neurotransmission and an increase in neuronal excitability, which can lead to the exacerbation of neurological disorders.

In conclusion, NAA80 is a protein that plays a critical role in cellular processes, including cell signaling, DNA repair, and metabolism. It is a key enzyme in the glycolysis pathway and the citric acid cycle, and it is involved in the regulation of cell growth, metabolism, and cancer cell growth and metastasis, as well as diabetes and neurological disorders. As a result, NAA80 is a potential drug target and biomarker for various diseases, including cancer,

Protein Name: N-alpha-acetyltransferase 80, NatH Catalytic Subunit

Functions: N-alpha-acetyltransferase that specifically mediates the acetylation of the acidic amino terminus of processed forms of beta- and gamma-actin (ACTB and ACTG, respectively) (PubMed:30028079, PubMed:29581253). N-terminal acetylation of processed beta- and gamma-actin regulates actin filament depolymerization and elongation (PubMed:29581253). In vivo, preferentially displays N-terminal acetyltransferase activity towards acid N-terminal sequences starting with Asp-Asp-Asp and Glu-Glu-Glu (PubMed:30028079, PubMed:29581253). In vitro, shows high activity towards Met-Asp-Glu-Leu and Met-Asp-Asp-Asp (PubMed:10644992, PubMed:29581307). May act as a tumor suppressor (PubMed:10644992)

The "NAA80 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NAA80 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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