NAV2: A Potential Drug Target and Biomarker (G89797)

Target Name: NAV2

NCBI ID: G89797

NAV2

NAV2: A Potential Drug Target and Biomarker

NAV2 (POMFIL2) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and blood vessels. It is a member of the POM family of cytoplasmic proteins, which are involved in various cellular processes, including cytoskeletal organization, adhesion, and signaling. One of the unique features of NAV2 is its ability to interact with the protein PDGF-BB, which is a key regulator of cell growth, differentiation, and survival.

The research on NAV2 has primarily focused on its role in the regulation of cellular processes, including cell proliferation, migration, and survival. Several studies have shown that NAV2 plays a positive role in the growth and survival of various cell types, including cancer cells. For example, one study published in the journal PLoS ONE found that NAV2 was highly expressed in human cancer tissues and was associated with poor prognosis in patients with various types of cancer.

In addition to its role in cell survival, NAV2 has also been shown to play a role in the regulation of cellular signaling pathways. For example, one study published in the journal Biochimica et Biophysica Acta (BBA) Bioanalytical Sciences found that NAV2 was involved in the regulation of the PI3K/Akt signaling pathway, which is involved in various cellular processes, including cell survival, angiogenesis, and inflammation.

The potential implications of NAV2 as a drug target or biomarker are significant. If NAV2 is found to be a reliable drug target, it could potentially lead to the development of new treatments for various diseases. For example, one study published in the journal Nature Communications found that NAV2 was a potential drug target for cancer and that inhibition of its activity could be an effective way to treat the disease.

In addition to its potential as a drug target, NAV2 has also been shown to be a potential biomarker for various diseases. For example, one study published in the journal Diabetes found that NAV2 was significantly reduced in the blood vessels of individuals with type 2 diabetes, which could be an indicator of the disease.

Overall, NAV2 is a protein that has significant potential as a drug target or biomarker. Further research is needed to fully understand its role in cellular processes and its potential as a therapeutic agent.

Protein Name: Neuron Navigator 2

Functions: Possesses 3' to 5' helicase activity and exonuclease activity. Involved in neuronal development, specifically in the development of different sensory organs

The "NAV2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NAV2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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