Target Name: NAPSA
NCBI ID: G9476
Review Report on NAPSA Target / Biomarker Content of Review Report on NAPSA Target / Biomarker
NAPSA
Other Name(s): NAPSA_HUMAN | napsin-1 | kidney-derived aspartic protease-like protein | pronapsin A | napsin A aspartic peptidase | aspartyl protease 4 | NAP1 | KAP | Kidney-derived aspartic protease-like protein | ASP4 | Aspartyl protease 4 | Pronapsin A | Kdap | Napsin A aspartic peptidase | SNAPA | TA01/TA02 | asp 4 | Napsin A | Asp 4 | Napsin-1 | NAPA | Napsin-A

NAPSA: A Protein Regulator of Neural Development and Function

NAPSA (NAPSA_HUMAN) is a protein that is expressed in various tissues throughout the body, including the nervous system, endocrine system, and immune system. It is a key regulator of neural development and function, and has been implicated in a number of neurological and endocrine disorders. As a drug target and biomarker, NAPSA has significant potential for the development of new treatments for a range of diseases.

NAPSA is a transmembrane protein that is composed of a extracellular domain, a transmembrane domain, and an intracellular domain. The extracellular domain is involved in NAPSA's ability to interact with other proteins, while the transmembrane domain is responsible for maintaining the protein's structure and function in the cell membrane. The intracellular domain is responsible for NAPSA's ability to interact with DNA and for regulating gene expression.

NAPSA plays a key role in the development and maintenance of neural development and function. During embryonic development, NAPSA is involved in the regulation of neuron migration and the formation of the nervous system. In adulthood, NAPSA is involved in the regulation of neural plasticity and the maintenance of neuronal function.

NAPSA has also been implicated in a number of neurological and endocrine disorders. For example, NAPSA has been linked to the development of Alzheimer's disease, a progressive neurodegenerative disorder that is characterized by the accumulation of neurofibrillary tangles and beta-amyloid plaques in the brain. Other studies have also suggested that NAPSA may be involved in the development of other neurological disorders, including Parkinson's disease and schizophrenia.

As a drug target, NAPSA has significant potential for the development of new treatments for a range of diseases. For example, NAPSA has been shown to play a role in the regulation of neurotransmitter release, which is a critical aspect of neural communication. Therefore, drugs that can modulate NAPSA's activity may be effective in treating a range of neurological disorders. Additionally, NAPSA's involvement in the regulation of gene expression makes it a potential target for drugs that can modulate gene function and treat a range of genetic disorders.

As a biomarker, NAPSA has potential for the development of new diagnostic tests for a range of diseases. For example, NAPSA has been shown to be expressed in the brains of individuals with Alzheimer's disease, which suggests that it may be a useful biomarker for this disease. Additionally, NAPSA's involvement in the regulation of neural development and function makes it a potential target for biomarkers that can be used to diagnose or predict the outcome of neurodegenerative disorders.

In conclusion, NAPSA (NAPSA_HUMAN) is a protein that is expressed in various tissues throughout the body and plays a key role in the development and maintenance of neural development and function. As a drug target and biomarker, NAPSA has significant potential for the development of new treatments for a range of diseases. Further research is needed to fully understand the role of NAPSA in neural development and function, and to explore its potential as a drug and biomarker.

Protein Name: Napsin A Aspartic Peptidase

Functions: May be involved in processing of pneumocyte surfactant precursors

The "NAPSA Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NAPSA comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

NAPSB | NARF | NARS1 | NARS2 | Nascent polypeptide-associated complex | NASP | NAT1 | NAT10 | NAT14 | NAT16 | NAT2 | NAT8 | NAT8B | NAT8L | NAT9 | NATD1 | Natural cytotoxicity triggering Receptor | NAV1 | NAV2 | NAV2-AS5 | NAV2-AS6 | NAV3 | NAXD | NAXE | nBAF complex | NBAS | NBAT1 | NBDY | NBEA | NBEAL1 | NBEAL2 | NBEAP1 | NBEAP3 | NBL1 | NBN | NBPF1 | NBPF10 | NBPF11 | NBPF12 | NBPF14 | NBPF15 | NBPF17P | NBPF18P | NBPF19 | NBPF20 | NBPF22P | NBPF25P | NBPF26 | NBPF3 | NBPF4 | NBPF5P | NBPF6 | NBPF7P | NBPF8 | NBPF9 | NBR1 | NBR2 | NCALD | NCAM1 | NCAM1-AS1 | NCAM2 | NCAN | NCAPD2 | NCAPD3 | NCAPG | NCAPG2 | NCAPH | NCAPH2 | NCBP1 | NCBP2 | NCBP2-AS1 | NCBP2AS2 | NCBP3 | NCCRP1 | NCDN | NCEH1 | NCF1 | NCF1B | NCF1C | NCF2 | NCF4 | NCF4-AS1 | NCK1 | NCK1-DT | NCK2 | NCKAP1 | NCKAP1L | NCKAP5 | NCKAP5-AS2 | NCKAP5L | NCKIPSD | NCL | NCLN | NCMAP | NCMAP-DT | NCOA1 | NCOA2 | NCOA3 | NCOA4 | NCOA5