NAF1 and NAP-2: Key Regulators of Nuclear Assembly and Cancer Development

Target Name: NAF1

NCBI ID: G92345

NAF1

NAF1 and NAP-2: Key Regulators of Nuclear Assembly and Cancer Development

Nuclear assembly factor 1 (NAF1) is a protein that plays a critical role in the process of nuclear assembly, which is the process by which the DNA of a cell is replicated and wrapped into a functional nucleus. NAF1 is a key regulator of this process and is involved in the formation of functional nuclei in the cell.

One of the unique features of NAF1 is its ability to form a stable complex with the protein cofilomerin, which is also known as NAF1-associated protein 2 (NAP-2). This complex plays a key role in the regulation of nuclear assembly and is a potential drug target for the development of cancer.

The NAF1-associated protein 2 (NAP-2) is a protein that is highly conserved across various species and is found in various cell types, including bacteria, yeast, and plants. It is known to interact with NAF1 and is involved in the regulation of various cellular processes, including cell division, DNA replication, and repair.

The NAF1-associated protein 2 (NAP-2) is a 21-kDa protein that is composed of 155 amino acid residues. It has a molecular weight of 21 kDa and a calculated pI of 12.9. It is found in various cellular compartments, including the cytoplasm, the endoplasmic reticulum, and the nuclear envelope.

The NAF1-associated protein 2 (NAP-2) is involved in the regulation of various cellular processes, including cell division, DNA replication, and repair. It is known to interact with various cellular components, including NAF1, histone (H1), Histone X (H1X), and ribolin R (RNP), etc.

One of the key functions of NAF1 is its ability to form a stable complex with NAP-2. This complex plays a key role in the regulation of nuclear assembly and is involved in the formation of functional nuclei in the cell. The NAF1-associated protein 2 (NAP-2) is a critical regulator of this process and is involved in the regulation of various cellular processes, including cell division, DNA replication, and repair.

The NAF1-associated protein 2 (NAP-2) is a potential drug target for the development of cancer. Its role in the regulation of nuclear assembly and its interaction with NAF1 make it an attractive target for small molecule inhibitors. Various studies have shown that Inhibitors of NAP-2 have the potential to inhibit the growth of cancer cells and to enhance the sensitivity of cancer cells to chemotherapy.

In addition to its role in the regulation of nuclear assembly, NAF1 is also involved in the regulation of various cellular processes, including cell division, DNA replication, and repair. It is known to interact with various cellular components, including NAF1, histones ( H1), histone X (H1X), and ribolin R (RNP), etc.

The NAF1 gene is located on chromosome 18 and encodes a protein of 1,900 amino acids. It is a member of the FERMT (F-type motor protein) family and is involved in the regulation of various cellular processes, including cell division, DNA replication, and repair.

NAF1 is a key regulator of the process of nuclear assembly, which is the process by which the DNA of a cell is replicated and wrapped into a functional nucleus. It is involved in the formation of functional nuclei in the cell and is a potential drug target for the development of cancer. The NAF1-associated protein 2 (

Protein Name: Nuclear Assembly Factor 1 Ribonucleoprotein

Functions: RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4

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