Target Name: NACA
NCBI ID: G4666
Review Report on NACA Target / Biomarker Content of Review Report on NACA Target / Biomarker
NACA
Other Name(s): Alpha-NAC | NACA variant 4 | nascent polypeptide associated complex subunit alpha | Nascent polypeptide-associated complex subunit alpha | Nascent polypeptide-associated complex subunit alpha (isoform b) | Nascent polypeptide associated complex subunit alpha, transcript variant 4 | HSD48 | NACA variant 3 | Nascent-polypeptide-associated complex alpha polypeptide | Nascent polypeptide associated complex subunit alpha, transcript variant 3 | NACA1 | NAC-alpha | Hom s 2 | NACA_HUMAN | skNAC | nascent-polypeptide-associated complex alpha polypeptide | MGC117224 | alpha-NAC, muscle-specific form

Understanding The Potential of NACA: A Non-Coding RNA Molecule

NACA (Alpha-NAC) is a protein that is expressed in various tissues throughout the body, including the brain, lungs, heart, kidneys, and gastrointestinal tract. It is a non-coding RNA molecule that has been shown to play a role in a variety of physiological processes in the body.

One of the most promising aspects of NACA is its potential as a drug target. NACA has been shown to interact with a variety of proteins, including the transcription factor ASXL1, which is involved in a variety of cellular processes, including cell growth, differentiation, and survival.

In addition to its potential as a drug target, NACA has also been shown to be a valuable biomarker for a variety of diseases. For example, NACA has been shown to be decreased in the brains of individuals with Alzheimer's disease, which is a degenerative brain disorder that is characterized by progressive memory loss and other cognitive impairments.

NACA has also been shown to be decreased in the blood of individuals with heart disease, which is a leading cause of death in adults. This suggests that NACA may be a useful biomarker for heart disease, and that its levels may be a useful target for diagnostic tests.

In addition to its potential as a drug target and biomarker, NACA is also of interest to researchers because of its unique structure and biology. NACA is a small RNA molecule that is expressed in high levels in many different tissues, but it is not a typical protein. This means that researchers have been able to study its biology at a level that is not possible with many other proteins.

One of the ways that researchers have studied NACA is through its function in the regulation of gene expression. NACA has been shown to interact with the RNA polymerase II, which is the enzyme that transcribes DNA into RNA. This suggests that NACA may be involved in the regulation of gene expression and that it may be a useful target for drugs that target RNA polymerase II.

Another way that researchers have studied NACA is through its role in the regulation of cellular processes. NACA has been shown to play a role in the regulation of cell adhesion, which is the process by which cells stick together and form tissues. This suggests that NACA may be involved in the regulation of cell adhesion and that it may be a useful target for drugs that target this process.

In conclusion, NACA is a protein that has been shown to play a role in a variety of physiological processes in the body. Its unique structure and biology make it an attractive target for drug research, and its potential as a biomarker for a variety of diseases makes it an important area of study. Further research is needed to fully understand the role of NACA in the regulation of gene expression and cellular processes, and to determine its potential as a drug target and biomarker.

Protein Name: Nascent Polypeptide Associated Complex Subunit Alpha

Functions: Cardiac- and muscle-specific transcription factor. May act to regulate the expression of genes involved in the development of myotubes. Plays a critical role in ventricular cardiomyocyte expansion and regulates postnatal skeletal muscle growth and regeneration. Involved in the organized assembly of thick and thin filaments of myofibril sarcomeres (By similarity)

The "NACA Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NACA comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

NACA2 | NACA3P | NACA4P | NACAD | NACC1 | NACC2 | NAD(P)H dehydrogenase, quinone | NAD-Dependent Protein Deacetylase | NADH dehydrogenase (Complex I) | NADK | NADK2 | NADPH Oxidase | NADPH Oxidase Complex | NADSYN1 | NAE1 | NAF1 | NAG18 | NAGA | NAGK | NAGLU | NAGPA | NAGPA-AS1 | NAGS | NAIF1 | NAIP | NAIPP2 | NALCN | NALCN sodium channel complex | NALCN-AS1 | NALF1 | NALF2 | NALT1 | NAMA | NAMPT | NAMPTP1 | NANOG | NANOGNB | NANOGP1 | NANOGP8 | NANOS1 | NANOS2 | NANOS3 | NANP | NANS | NAP1L1 | NAP1L1P1 | NAP1L2 | NAP1L3 | NAP1L4 | NAP1L4P1 | NAP1L5 | NAP1L6P | NAPA | NAPA-AS1 | NAPB | NAPEPLD | NAPG | NAPRT | NAPSA | NAPSB | NARF | NARS1 | NARS2 | Nascent polypeptide-associated complex | NASP | NAT1 | NAT10 | NAT14 | NAT16 | NAT2 | NAT8 | NAT8B | NAT8L | NAT9 | NATD1 | Natural cytotoxicity triggering Receptor | NAV1 | NAV2 | NAV2-AS5 | NAV2-AS6 | NAV3 | NAXD | NAXE | nBAF complex | NBAS | NBAT1 | NBDY | NBEA | NBEAL1 | NBEAL2 | NBEAP1 | NBEAP3 | NBL1 | NBN | NBPF1 | NBPF10 | NBPF11 | NBPF12 | NBPF14 | NBPF15