Target Name: SHPRH
NCBI ID: G257218
Review Report on SHPRH Target / Biomarker Content of Review Report on SHPRH Target / Biomarker
SHPRH
Other Name(s): SHPRH_HUMAN | RAD5 | SNF2 histone linker PHD RING helicase | SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase | SHPRH variant 1 | bA545I5.2 | SNF2 histone linker PHD RING helicase, transcript variant 1 | SNF2, histone-linker, PHD and RING finger domain-containing helicase | E3 ubiquitin-protein ligase SHPRH | RING-type E3 ubiquitin transferase SHPRH | 2610103K11Rik | KIAA2023 | E3 ubiquitin-protein ligase SHPRH (isoform a)

SHPRH: A Protein Targeted for Drug and Biomarker Development

SHPRH (short for SHPRH_HUMAN) is a protein that is expressed in human tissues and has been shown to play a role in a variety of biological processes. Several studies have suggested that SHPRH may be a drug target or biomarker, and research is ongoing to determine its potential utility in these areas.

The SHPRH protein is a member of the tyrosine kinase family and is expressed in a variety of human tissues, including muscle, heart, and brain. It is involved in the regulation of cell proliferation and has been shown to play a role in the development and progression of several diseases, including cancer.

One of the key functions of SHPRH is its role in cell signaling. SHPRH has been shown to be involved in the regulation of cell proliferation and cell survival, and it has been shown to play a role in the development of cancer. For example, studies have shown that SHPRH can promote the growth and survival of cancer cells, and that inhibiting its activity can be an effective way to treat cancer.

Another function of SHPRH is its role in inflammation. SHPRH has been shown to be involved in the regulation of inflammation and has been shown to play a role in the development of several inflammatory diseases, including arthritis and asthma.

In addition to its role in cell signaling and inflammation, SHPRH has also been shown to be involved in the regulation of stem cell proliferation. SHPRH has been shown to play a role in the regulation of stem cell self-renewal and has been shown to play a role in the development of cancer.

Given its involvement in so many different functions, it is not surprising that SHPRH has been identified as a potential drug target or biomarker. Several studies have shown that SHPRH can be targeted by small molecules and that modifying its activity may be an effective way to treat a variety of diseases.

One of the most promising areas of research is the study of SHPRH as a drug target. Studies have shown that SHPRH can be targeted by small molecules, including inhibitors of tyrosine kinase activity, and that modifying its activity may be an effective way to treat a variety of diseases. For example, studies have shown that inhibiting SHPRH activity can be an effective way to treat cancer, and that modulating its activity may be an effective way to treat other diseases, such as arthritis and asthma.

In addition to its potential as a drug target, SHPRH has also been identified as a potential biomarker. Studies have shown that SHPRH is expressed in a variety of human tissues and that its levels can be used as a diagnostic marker for several diseases, including cancer. In addition, SHPRH has been shown to be involved in the regulation of cell signaling and inflammation, which makes it an attractive candidate for use as a biomarker for diseases associated with these processes.

Overall, SHPRH is a protein that has been shown to play a role in a variety of biological processes and has been identified as a potential drug target or biomarker. Further research is needed to fully understand its functions and to determine its potential utility in treating disease.

Protein Name: SNF2 Histone Linker PHD RING Helicase

Functions: E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'

The "SHPRH Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SHPRH comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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