Target Name: MPC2
NCBI ID: G25874
Review Report on MPC2 Target / Biomarker Content of Review Report on MPC2 Target / Biomarker
MPC2
Other Name(s): MPC2_HUMAN | MPC2 variant 2 | Mitochondrial pyruvate carrier 2 (MPC2), transcript variant 1 | OTTHUMP00000032518 | MGC125752 | BRP44 | MPC2 variant 1 | MPC-2 | Mitochondrial pyruvate carrier 2 | SLC54A2 | DKFZp564B167 | MGC125753 | brain protein 44 | Mitochondrial pyruvate carrier 2, transcript variant 2 | mitochondrial pyruvate carrier 2 | Brain protein 44

MPC2: A Protein Involved in Immune System Regulation and Cancer Therapy

MPC2 (MPC2_HUMAN), also known as CD28, is a protein that is expressed in various tissues of the human body, including the immune system, and is involved in cell-mediated immunity. It is a member of the CD28 superfamily, which includes several other proteins that play a crucial role in the immune response.

MPC2 is a 21-kDa protein that is expressed in various tissues of the human body, including the spleen, Peyer's patches, and the skin. It is involved in cell-mediated immunity, as well as in the regulation of inflammation and autoimmunity.

One of the key functions of MPC2 is its role in the regulation of T cell activation and proliferation. T cells are a crucial part of the immune system, and they play a key role in fighting off infections and cancer. MPC2 helps to regulate the activation and proliferation of T cells, ensuring that they are able to effectively carry out their important role in maintaining the immune system.

Another important function of MPC2 is its role in the regulation of immune cell interactions. MPC2 helps to regulate the interactions between T cells and other immune cells, ensuring that they are able to work together effectively in the fight against infections and cancer.

MPC2 is also involved in the regulation of inflammation and autoimmunity. It helps to regulate the production of antibodies and other immune molecules, as well as the activation and proliferation of immune cells. This helps to keep the immune system under control and prevent it from causing unnecessary inflammation or autoimmunity.

In addition to its role in immune system regulation, MPC2 is also involved in the regulation of cell-mediated immunity. It helps to regulate the production of cytokines, which are important molecules that help to coordinate the immune response. This helps to ensure that the immune system is able to effectively respond to the presence of foreign substances in the body.

MPC2 is also a potential drug target and biomarker. Several studies have suggested that MPC2 may be a useful target for cancer therapy, particularly for melanoma. By inhibiting the activity of MPC2, it may be possible to kill cancer cells that have been affected by the disease. Additionally, MPC2 has also been suggested as a potential biomarker for monitoring the effectiveness of cancer treatment. By measuring the levels of MPC2 in cancer cells, it may be possible to determine whether treatment is having the desired effect.

In conclusion, MPC2 is a protein that is involved in various aspects of the immune system and the regulation of inflammation and autoimmunity. It is a potential drug target and biomarker, and its role in the immune system may be an important target for cancer therapy. Further research is needed to fully understand the functions of MPC2 and its potential as a drug and biomarker.

Protein Name: Mitochondrial Pyruvate Carrier 2

Functions: Mediates the uptake of pyruvate into mitochondria

The "MPC2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MPC2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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