Target Name: MPDZ
NCBI ID: G8777
Review Report on MPDZ Target / Biomarker Content of Review Report on MPDZ Target / Biomarker
MPDZ
Other Name(s): MPDZ variant 2 | HYC2 | Multiple PDZ domain crumbs cell polarity complex component, transcript variant 1 | MPDZ_HUMAN | Multiple PDZ domain protein (isoform 1) | multiple PDZ domain crumbs cell polarity complex component | multi-PDZ domain protein 1 | Multiple PDZ domain crumbs cell polarity complex component, transcript variant 4 | Multiple PDZ domain protein (isoform 4) | Multiple PDZ domain crumbs cell polarity complex component, transcript variant 5 | MPDZ variant 4 | Multiple PDZ domain protein isoform 5 | Multi-PDZ domain protein 1 | MPDZ variant 1 | Multiple PDZ domain crumbs cell polarity complex component, transcript variant 2 | MPDZ variant 5 | MUPP1 | Multiple PDZ domain protein (isoform 2) | Multiple PDZ domain protein

Unlocking The Function of MPDZ: A Potential Drug Target for Neurological Disorders

MPDZ (MPDZ variant 2) is a protein that is expressed in the brain and has been shown to play a role in the development and progression of several neurological disorders, including Alzheimer's disease, Parkinson's disease, and multiple sclerosis. The exact function of MPDZ is not yet fully understood, but it is thought to be involved in the regulation of synaptic plasticity, which is the ability of the brain to learn and adapt over time.

One of the key challenges in studying MPDZ is its complex structure and the difficulty in recreating it in the laboratory. However, researchers have been able to identify several unique features of the protein that make it an attractive drug target.

One of the most notable features of MPDZ is its ability to interact with several different signaling pathways in the brain. This allows it to influence a wide range of cellular processes, including the regulation of neurotransmitter release, the formation of neural connections, and the regulation of inflammation.

Another key feature of MPDZ is its role in the regulation of synaptic plasticity. This is an important process that allows the brain to adapt and learn new things, and is thought to be involved in the development of several neurological disorders. Researchers have shown that MPDZ plays a key role in the regulation of synaptic plasticity, by participating in the formation of new neural connections and the modification of existing ones.

In addition to its role in synaptic plasticity, MPDZ is also thought to be involved in the regulation of the immune system. This is an important function of the immune system, and is thought to be involved in the development of several neurological disorders. Researchers have shown that MPDZ interacts with immune cells and that this interaction may play a role in the development of autoimmune disorders.

Despite these promising findings, much work remains to be done in order to fully understand the function of MPDZ. Researchers are still trying to determine exactly how the protein functions and how it contributes to the development and progression of neurological disorders. However, the study of MPDZ is an important area of research, as it has the potential to lead to new and effective treatments for a wide range of disorders.

Protein Name: Multiple PDZ Domain Crumbs Cell Polarity Complex Component

Functions: Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses (PubMed:11150294, PubMed:15312654). Promotes clustering of HT2RC at the cell surface (By similarity)

The "MPDZ Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MPDZ comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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