Identifying FBXW4P1 as A Potential Drug Target for Neurodegenerative Diseases

Target Name: FBXW4P1

NCBI ID: G26226

FBXW4P1

Other Name(s): FBW3 | F-box and WD repeat domain containing 4 pseudogene 1 | SHFM3P1 | FBXW3

Identifying FBXW4P1 as A Potential Drug Target for Neurodegenerative Diseases

FBXW4P1, also known as FBW3, is a protein that is found in the endoplasmic reticulum (ER) and is involved in the regulation of protein stability and degradation. FBXW4P1 has been identified as a potential drug target and is a focus of research in the field of neurodegenerative diseases.

The endoplasmic reticulum is a membrane-enclosed organelle that contains many important proteins, including those related to cell metabolism and function. FBXW4P1 is one of the proteins, which is involved in regulating the stability, stability and degradation of proteins and is an important metabolic process in cells.

The protein encoded by the FBXW4P1 gene is an approximately 120 amino acid polypeptide chain, and its unique domain structure makes it an attractive research object. Its unique domain structure includes a short tail domain, which is one of the common protein domains, as well as a long N-terminal 伪-helix and B-terminal 尾-helix. These domains make it highly specific and can bind to other proteins.

The role of FBXW4P1 in neurodegenerative diseases

Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease, are common neurological disorders that cause symptoms such as cognitive impairment, muscle weakness, and insomnia. The main cause of these diseases is the death or damage of neurons, leading to neuronal damage. Therefore, it is of great significance to study the role of FBXW4P1 in neurodegenerative diseases.

Research shows that FBXW4P1 plays an important role in neurodegenerative diseases. Studies have shown that levels of FBXW4P1 have been reduced in individuals with neurodegenerative diseases, and its levels have been increased in individuals with neurodegenerative diseases compared to age-matched individuals. Additionally, studies have shown that FBXW4P1 levels have been reduced in the brains of individuals with neurodegenerative diseases. These data suggest that FBXW4P1 plays an important role in neurodegenerative diseases and may be a potential drug target.

FBXW4P1 as a drug target

Protein Name: F-box And WD Repeat Domain Containing 4 Pseudogene 1

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•   expression level;
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