OR8B3 Receptor: A Protein Implicated in Human Olfactory System and Drug Development
OR8B3 Receptor: A Protein Implicated in Human Olfactory System and Drug Development
OR8B3 (Olfactory Receptor OR11-311) is a protein that is expressed in the olfactory system, which is responsible for the sense of smell. OR8B3 is a G protein-coupled receptor (GPCR), which is a type of transmembrane protein that plays an important role in cellular signaling. GPCRs are a family of proteins that are involved in a wide range of physiological processes, including sensory perception, neurotransmitter signaling, and hormone regulation.
The olfactory system is one of the most complex systems that are involved in human sensory perception. The olfactory system consists of over 400 olfactory epithelial cells, each of which has a different olfactory receptor type. These olfactory epithelial cells express two main types of olfactory epithelial cell receptors: type 1 (OR1R1 and OR1R2) and type 2 (OR1R3 and OR1R4). Among them, the proteins expressed by type 1 receptors are called type 1 olfactory epithelial cell receptors, while the proteins expressed by type 2 receptors are called type 2 olfactory epithelial cell receptors.
OR8B3 is a type 1 olfactory epithelial cell receptor and is a protein encoded on the human chromosome. The OR8B3 receptor gene is located on chromosome Xp11.1 in the human genome. The protein encoded by the OR8B3 receptor gene is a 126-amino-acid polypeptide with a molecular weight of 17.1 kDa.
The OR8B3 receptor plays an important role in human olfactory physiology. In humans, variations in the OR8B3 receptor gene are associated with many types of sinusitis, including allergic rhinitis, and the severity of sinusitis. In addition, variations in the OR8B3 receptor gene are also associated with the onset of Alzheimer's disease.
In recent years, researchers have discovered the potential role of the OR8B3 receptor in drug development. OR8B3 receptors are a good drug target because of their targetability in drug responses. Due to the targetability of the OR8B3 receptor in drug responses, researchers are exploring the OR8B3 receptor as a drug target to treat a variety of
Protein Name: Olfactory Receptor Family 8 Subfamily B Member 3
Functions: Odorant receptor
The "OR8B3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR8B3 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
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